CAS 124832-27-5: Valacyclovir hydrochloride
Description:Valacyclovir hydrochloride is an antiviral medication primarily used to treat infections caused by certain types of viruses, including herpes simplex virus and varicella-zoster virus. It is the L-valyl ester of acyclovir, which enhances its bioavailability when administered orally. The substance appears as a white to off-white crystalline powder and is soluble in water, making it suitable for formulation in various dosage forms. Valacyclovir hydrochloride works by inhibiting viral DNA synthesis, thereby preventing the replication of the virus. Its pharmacokinetics indicate that it is rapidly converted to acyclovir in the body, which is the active form responsible for its therapeutic effects. The compound is typically administered in tablet form and is well-tolerated, although potential side effects may include gastrointestinal disturbances and headache. As with any antiviral treatment, it is essential to use valacyclovir hydrochloride under medical supervision to ensure appropriate dosing and to monitor for any adverse reactions.
Formula:C13H20N6O4·ClH
InChI:InChI=1S/C13H20N6O4.ClH/c1-7(2)8(14)12(21)23-4-3-22-6-19-5-16-9-10(19)17-13(15)18-11(9)20;/h5,7-8H,3-4,6,14H2,1-2H3,(H3,15,17,18,20);1H/t8-;/m0./s1
InChI key:InChIKey=ZCDDBUOENGJMLV-QRPNPIFTSA-N
SMILES:Cl.O=C1N=C(N)NC2=C1N=CN2COCCOC(=O)C(N)C(C)C
- Synonyms:
- l-valine 2-[(2-amino-1,6-dihydro-6-oxo-9h-purin-9yl)methoxy]ethyl ester, hydrochlroride salt
- l-valine 2-[(2-amino-1,6-dihydro-6-oxo-9h-purin-9yl)methoxy]ethyl ester, hydrochloride salt
- Valacyclovir hcl
- 2-[(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)methoxy]ethyl L-valinate hydrochloride (1:1)
- BW 256U87
- Valacyclovir hydrochloride
- 2-[(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)methoxy]ethyl L-valinate
- valacyclovir hydrochloride
- valaciclovir hydrochloride
- L-Valine, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]ethyl ester, hydrochloride (1:1)
- See more synonyms
- l-valine -2-[(2-amino-1,6-dihydro-6-oxo-9h-purin-9-yl) methoxy]ethylester monohydrochloride
- valacyclover hydrochloric
- valacycloverhydrochloride
- l-valine, 2-[(2-amino-1,6-dihydro-6-oxo-9h-purin-9-yl)methoxy]ethyl ester, monohydrochloride
- 256U87 hydrochloride
- 9-((2-hydroxy-ethoxy)methyl)guanine l-valine ester hydrochloride
- L-Valine, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]ethyl ester, monohydrochloride
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