CAS 124937-51-5

Tolterodine

Description:

Tolterodine is a pharmaceutical compound primarily used as an antimuscarinic agent for the treatment of overactive bladder. It functions by selectively blocking muscarinic receptors, which helps reduce involuntary bladder contractions and urinary urgency. The chemical formula of tolterodine is C19H25N, and it has a molecular weight of approximately 281.42 g/mol. This substance is typically administered in the form of its tartrate salt, which enhances its solubility and bioavailability. Tolterodine is characterized by its moderate lipophilicity, allowing it to cross biological membranes effectively. It exhibits a relatively long half-life, which supports once-daily dosing in clinical settings. Common side effects may include dry mouth, constipation, and dizziness, reflecting its anticholinergic properties. Due to its mechanism of action, tolterodine is contraindicated in patients with certain conditions, such as narrow-angle glaucoma or urinary retention. Overall, tolterodine represents a significant advancement in the management of urinary disorders, providing symptomatic relief for patients with overactive bladder syndrome.

Formula: C₂₂H₃₂ClNO

InChI: InChI=1/C22H31NO.ClH/c1-16(2)23(17(3)4)14-13-20(19-9-7-6-8-10-19)21-15-18(5)11-12-22(21)24;/h6-12,15-17,20,24H,13-14H2,1-5H3;1H

InChI key: InChIKey=OOGJQPCLVADCPB-HXUWFJFHSA-N

SMILES: [C@H](CCN(C(C)C)C(C)C)(C1=C(O)C=CC(C)=C1)C2=CC=CC=C2

Synonyms:

• 124937-51-5
• 2-[3-(dipropan-2-ylamino)-1-phenylpropyl]-4-methylphenol
• 2-[(1R)-3-(dipropan-2-ylamino)-1-phenylpropyl]-4-methylphenol 2,3-dihydroxybutanedioate (1:1)
• phenol, 2-[3-[bis(1-methylethyl)amino]-1-phenylpropyl]-4-methyl-
• 2-{3-[bis(1-methylethyl)amino]-1-phenylpropyl}-4-methylphenol
• 2-[(1S)-3-(dipropan-2-ylamino)-1-phenylpropyl]-4-methylphenol
• 2-[3-(diisopropylamino)-1-phenyl-propyl]-4-methyl-phenol hydrochloride

2-[(1R)-3-[bis(propan-2-yl)amino]-1-phenylpropyl]-4-methylphenol

CAS: 124937-51-5

Formula: C₂₂H₃₁NO

Purity: 99%

Color and Shape: Solid

Molecular weight: 325.4876

Ref: IN-DA000MWB

Tolterodine

CAS: 124937-51-5

Tolterodine

Purity: ≥98%

Molecular weight: 325.49g/mol

Ref: 54-BUP06316

Tolterodine Tartrate

CAS: 124937-51-5, 124937-52-6

Formula: C₂₂H₃₁NO·C₄H₆O₆

Color and Shape: White To Off-White Solid

Molecular weight: 325.50 150.09

Ref: 4Z-T-176

Tolterodine

CAS: 124937-51-5

Tolterodine ((R)-(+)-Tolterodine) is an mACh antagonist used in the treatment of detrusor instability and overactive bladder syndrome.

Formula: C₂₂H₃₁NO

Purity: 99.71%

Color and Shape: White Like Or Light Brown Crystalline Powder

Molecular weight: 325.49

Ref: TM-T23229

TOLTERODINE

CAS: 124937-51-5

Purity: 99%

Molecular weight: 325.4960022

Ref: 10-F805159

R-(+)-Tolterodine

CAS: 124937-51-5

Tolterodine is a drug that acts as a selective antagonist at the muscarinic receptor M3. It is used in the treatment of overactive bladder and other patients with bowel disease. Tolterodine has been shown to be effective in both animal models and humans for the treatment of overactive bladder. The mechanism of action of tolterodine is not fully understood, but it may involve blockade of postsynaptic M3 receptors in the bladder, leading to relaxation of smooth muscle and decreased contractility. Tolterodine is metabolized by various enzymes, including CYP2D6 and CYP3A4, which are primarily found in the liver and gut respectively. To date, there have been no reports of drug interactions between tolterodine and other drugs metabolized by these enzymes.

Formula: C₂₂H₃₁NO

Purity: Min. 95%

Molecular weight: 325.49 g/mol

Ref: 3D-FT28311