CAS 125-33-7

Primidone

Description:

Primidone is an anticonvulsant medication primarily used in the treatment of epilepsy and essential tremors. It is a white to off-white crystalline powder that is soluble in water and alcohol, with a molecular formula that reflects its organic nature. The substance acts as a prodrug, being metabolized in the liver to phenobarbital, which contributes to its therapeutic effects. Primidone exhibits a mechanism of action that involves the modulation of neurotransmitter activity, particularly enhancing GABAergic transmission, which helps stabilize neuronal excitability. Its pharmacokinetics include oral administration, with a relatively long half-life, allowing for once or twice daily dosing. Common side effects may include sedation, dizziness, and gastrointestinal disturbances. Due to its potential for dependence and withdrawal symptoms, careful monitoring is essential during treatment. Primidone is classified under the category of barbiturates, and its use should be approached with caution, particularly in patients with a history of substance abuse or certain medical conditions.

Formula: C₁₂H₁₄N₂O₂

InChI: InChI=1S/C12H14N2O2/c1-2-12(9-6-4-3-5-7-9)10(15)13-8-14-11(12)16/h3-7H,2,8H2,1H3,(H,13,15)(H,14,16)

InChI key: InChIKey=DQMZLTXERSFNPB-UHFFFAOYSA-N

SMILES: C(C)C1(C(=O)NCNC1=O)C2=CC=CC=C2

Synonyms:

• 2-Deoxyphenobarbital
• 2-Desoxyphenobarbital
• 5-Ethyl-5-phenyl-1,3-diazinane-4,6-dione
• 5-Ethyl-5-phenylhexahydropyrimidine-4,6-dione
• 5-Ethyldihydro-5-phenyl-4,6(1H,5H)-pyrimidinedione
• 5-Ethylhexahydro-5-phenylpyrimidine-4,6-dione
• 5-Phenyl-5-ethyl-hexahydropyrimidine-4,6-dione
• Hexamidine
• Hexamidine (antiepileptic)
• Hexamydin
• Lepimidin
• Liskantin
• Milepsin
• Misodine
• Misolyne
• Mizodin
• Mizolin
• Mylepsin
• Mysedon
• Mysoline
• Neurosyn
• Nsc 41701
• Primaclone
• Primacone
• Primakton
• Primidon
• Primidona
• Primidone
• Pyrimidone Medi-pets
• Resimatil
• Roe 101
• Sertan
• 5-ethyl-5-phenyldihydropyrimidine-4,6(1H,5H)-dione
• 4,6(1H,5H)-Pyrimidinedione, 5-ethyldihydro-5-phenyl-
• 5-ethyl-5-phenylperhydropyrimidine-4,6-dione
• Cyral
• 5-Phenyl-5-aethylhexahydropyrimidindion-(4,6)
• 5h)-pyrimidinedione,5-ethyldihydro-5-phenyl-6(1h
• 5-ethylhexahydro-4,6-dioxo-5-phenylphrimidine
• 5-Aethyl-5-phenyl-hexahydropyrimidin-4,6-dion
• 5-Ethylhexahydro-4,6-dioxo-5-phenylpyrimidine
• 5-Ethyl-5-phenyldihydro-4,6(1H,5H)-pyrimidinedione
• hexamidine(theantispasmodic)
• Desoxyphenobarbitone

Primidone

CAS: 125-33-7

Formula: C₁₂H₁₄N₂O₂

Purity: >98.0%(HPLC)(N)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 218.26

Ref: 3B-P1906

PRIMIDONE CRS

CAS: 125-33-7

PRIMIDONE CRS

Formula: C₁₂H₁₄N₂O₂

Color and Shape: Powder

Molecular weight: 218.2518

Ref: 41-P2950000

Primidone

CAS: 125-33-7

Primidone

Formula: C₁₂H₁₄N₂O₂

Purity: 99.6%

Color and Shape: White Crystalline Powder

Molecular weight: 218.10553

Ref: 47-293

Primidone

CAS: 125-33-7

Drugs containing a pyrimidine ring (whether or not hydr

Formula: C₁₂H₁₄N₂O₂

Color and Shape: White Powder

Molecular weight: 218.25

Ref: 45-1562000

Primidone

CAS: 125-33-7

Primidone (NCI-C56360) is a potent anticonvulsant agent.

Formula: C₁₂H₁₄N₂O₂

Purity: 99.91%

Color and Shape: Crystals (Ntp 1992)

Molecular weight: 218.25

Ref: TM-T0024

PRIMIDONE

CAS: 125-33-7

Formula: C₁₂H₁₄N₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 218.2518

Ref: IN-DA003TYH

Primidone

CAS: 125-33-7

Primidone

Purity: ≥98%

Molecular weight: 218.25g/mol

Ref: 54-BUP16549

Primidone

CAS: 125-33-7

Formula: C₁₂H₁₄N₂O₂

Color and Shape: White To Off-White Solid

Molecular weight: 218.26

Ref: 4Z-P-351

Primidone

CAS: 125-33-7

Primidone

Purity: 98%

Molecular weight: 218.25g/mol

Ref: 54-OR1029285

Primidone

CAS: 125-33-7

Formula: C₁₂H₁₄N₂O₂

Purity: ≥ 98.0%

Color and Shape: White to almost white powder or crystal

Molecular weight: 218.25

Ref: 7W-GP3317

Primidone

CAS: 125-33-7

Formula: C₁₂H₁₄N₂O₂

Color and Shape: Neat

Molecular weight: 218.25

Ref: 86-MM1030.00

Primidone (Standard)

CAS: 125-33-7

Primidone (Standard) is the standard substance of Primidone, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Primidone (NCI-C56360) is a potent anticonvulsant agent. It is a neuronal voltage-gated sodium channel blocker and has value in the study of epilepsy, essential tremor, and psychiatric disorders.

Formula: C₁₂H₁₄N₂O₂

Molecular weight: 218.25

Ref: TM-TMSM-1945

Primidone

CAS: 125-33-7

Formula: C₁₂H₁₄N₂O₂

Color and Shape: Neat

Molecular weight: 218.25

Ref: 04-C16287500

Primidone RS

CAS: 125-33-7

Color and Shape: White

Ref: 2K-1130000021

Primidone

CAS: 125-33-7

Applications Primidone is an Anticonvulsant.
References Bogue, C., et al.: Br. J. Pharmacol., 8, 230 (1953), Daley, R.D., Anal. Profiles Drug Subs., 2, 409 (1973),

Formula: C₁₂H₁₄N₂O₂

Color and Shape: White To Off-White

Molecular weight: 218.25

Ref: TR-P734000

Primidone

Controlled Product

CAS: 125-33-7

Melastatin-related transient receptor potential channel 3 antagonist

Formula: C₁₂H₁₄N₂O₂

Purity: Min. 98 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 218.25 g/mol

Ref: 3D-FP05584

Primidone - Bio-X ™

Controlled Product

CAS: 125-33-7

Primidone is an antiepileptic drug that is used to treat seizures. This drug alters transmembrane sodium and calcium channel transport, which in return reduces the frequency of nerve firing.

Formula: C₁₂H₁₄N₂O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 218.25 g/mol

Ref: 3D-BP166193

Primidone

CAS: 125-33-7

Color and Shape: Neat

Ref: 61-FOR1030.00