CAS 125-69-9

Dextromethorphan hydrobromide

Description:

Dextromethorphan hydrobromide is a synthetic compound primarily used as a cough suppressant in over-the-counter medications. It is an opioid derivative, specifically a morphinan, but it does not possess the analgesic properties typical of opioids. This substance acts on the central nervous system, specifically targeting the cough center in the brain to reduce the urge to cough. Dextromethorphan hydrobromide is typically administered in the form of tablets, syrups, or lozenges and is known for its relatively low potential for abuse compared to other cough suppressants. Physically, it is a white to off-white crystalline powder that is soluble in water and alcohol. The compound is generally well-tolerated, but excessive doses can lead to side effects such as dizziness, nausea, and in some cases, dissociative effects. It is important to use this medication as directed, as misuse can lead to serious health risks. Additionally, it is contraindicated in certain populations, including those taking monoamine oxidase inhibitors (MAOIs).

Formula: C₁₈H₂₅NO·BrH

InChI: InChI=1S/C18H25NO.BrH/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18;/h6-7,12,15,17H,3-5,8-11H2,1-2H3;1H/t15-,17+,18+;/m1./s1

InChI key: InChIKey=MISZALMBODQYFT-URVXVIKDSA-N

SMILES: O(C)C=1C=C2[C@]34[C@@]([C@](CC2=CC1)(N(C)CC3)[H])(CCCC4)[H].Br

Synonyms:

• (+)-3-Methoxy-17-methyl-morphinan hydrobromide
• (9Alpha,13Alpha,14Alpha)-3-Methoxy-17-Methylmorphinan Hydrobromide
• (9Alpha,13Alpha,14Alpha)-3-Methoxy-17-Methylmorphinan Hydrobromide Hydrate
• 3-Methoxy-17-Methylmorphinan Hydrobromide
• 9α,13α,14α-Morphinan, 3-methoxy-17-methyl-, hydrobromide
• Alpha-dextromethorphan
• Antussan
• Codiphan
• Coldex-D
• Colfed
• Delsym
• Demorphan
• Demorphine
• Destromethorphan hydrobromide
• Detosiv Slow Release
• Dextromethorphan bromide
• Dextromethorphan maleate HBR
• Dextroramin P
• Dormetan
• Dormethan
• Medicon
• Methorate hydrobromide
• Metrorat
• Morphinan, 3-methoxy-17-methyl-, hydrobromide (1:1), (9α,13α,14α)-
• Morphinan, 3-methoxy-17-methyl-, hydrobromide, (9α,13α,14α)-
• Nocuf
• Ro 1-5470
• Romilar
• Tosse Sedativo
• Tusilan
• Tussade
• d-3-Methoxy-N-methylmorphinan hydrobromide
• d-Methorphan hydrobromide

Dextromethorphan hydrobromide

CAS: 125-69-9

It is used as a potentially useful NMDA receptor agonist. it is usually used as central nervous antitussive, cough suppressant. This is one of the most popular ingredients in over-the-counter cold and cough medications. Dextromethorphan hydrobromide may be added to other preparations to help treat

Formula: C₁₈H₂₆BrNO

Color and Shape: White, Crystalline powder

Molecular weight: 352.32

Ref: 02-J61732

Dextromethorphan HBr

CAS: 125-69-9

Formula: C₁₈H₂₅NO·HBr

Color and Shape: White To Off-White Solid

Molecular weight: 271.40 80.91

Ref: 4Z-D-0310

D-Methorphan hydrobromide

Controlled Product

CAS: 125-69-9

Formula: C₁₈H₂₅NO·BrH

Color and Shape: Neat

Molecular weight: 352.31

Ref: 04-C15053000

Dextromethorphan-13C-d3 HBr

CAS: 125-69-9

Formula: C₁₇₁₃CH₂₂D₃NO·HBr

Molecular weight: 261.39 80.91

Ref: 4Z-D-0332

Dextromethorphan hydrobromide

Controlled Product

CAS: 125-69-9

Dextromethorphan hydrobromide is a drug that has been used to treat cough and cold symptoms. It is also an NMDA receptor antagonist, which blocks the activity of the NMDA receptor. Dextromethorphan hydrobromide is metabolized by the liver into dextrorphan and 3-methoxymorphinan, which are both active metabolites. Dextrorphan is a more potent NMDA receptor antagonist than dextromethorphan. The elimination half-life for dextrorphan is about 2 hours, whereas the elimination half-life for dextromethorphan is about 8 hours. The concentration–time curve for dextrorphan has been shown to be sigmoidal with a long tail, whereas the concentration–time curve for dextromethorphan has been shown to be linear with no long tail. Dextrorphan binds to adenosine A3 receptors in a competitive manner and has been shown

Formula: C₁₈H₂₅NO·HBr

Purity: Min. 95%

Molecular weight: 352.31 g/mol

Ref: 3D-FD146330