CAS 125-69-9
:Dextromethorphan hydrobromide
Description:
Dextromethorphan hydrobromide is a synthetic compound primarily used as a cough suppressant in over-the-counter medications. It is an opioid derivative, specifically a morphinan, but it does not possess the analgesic properties typical of opioids. This substance acts on the central nervous system, specifically targeting the cough center in the brain to reduce the urge to cough. Dextromethorphan hydrobromide is typically administered in the form of tablets, syrups, or lozenges and is known for its relatively low potential for abuse compared to other cough suppressants. Physically, it is a white to off-white crystalline powder that is soluble in water and alcohol. The compound is generally well-tolerated, but excessive doses can lead to side effects such as dizziness, nausea, and in some cases, dissociative effects. It is important to use this medication as directed, as misuse can lead to serious health risks. Additionally, it is contraindicated in certain populations, including those taking monoamine oxidase inhibitors (MAOIs).
Formula:C18H25NO·BrH
InChI:InChI=1S/C18H25NO.BrH/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18;/h6-7,12,15,17H,3-5,8-11H2,1-2H3;1H/t15-,17+,18+;/m1./s1
InChI key:InChIKey=MISZALMBODQYFT-URVXVIKDSA-N
SMILES:O(C)C=1C=C2[C@]34[C@@]([C@](CC2=CC1)(N(C)CC3)[H])(CCCC4)[H].Br
Synonyms:- (+)-3-Methoxy-17-methyl-morphinan hydrobromide
- (9Alpha,13Alpha,14Alpha)-3-Methoxy-17-Methylmorphinan Hydrobromide
- (9Alpha,13Alpha,14Alpha)-3-Methoxy-17-Methylmorphinan Hydrobromide Hydrate
- 3-Methoxy-17-Methylmorphinan Hydrobromide
- 9α,13α,14α-Morphinan, 3-methoxy-17-methyl-, hydrobromide
- Alpha-dextromethorphan
- Antussan
- Codiphan
- Coldex-D
- Colfed
- Delsym
- Demorphan
- Demorphine
- Destromethorphan hydrobromide
- Detosiv Slow Release
- Dextromethorphan bromide
- Dextromethorphan maleate HBR
- Dextroramin P
- Dormetan
- Dormethan
- Medicon
- Methorate hydrobromide
- Metrorat
- Morphinan, 3-methoxy-17-methyl-, hydrobromide (1:1), (9α,13α,14α)-
- Morphinan, 3-methoxy-17-methyl-, hydrobromide, (9α,13α,14α)-
- Nocuf
- Ro 1-5470
- Romilar
- Tosse Sedativo
- Tusilan
- Tussade
- d-3-Methoxy-N-methylmorphinan hydrobromide
- d-Methorphan hydrobromide
- See more synonyms
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Found 5 products.
Dextromethorphan hydrobromide
CAS:<p>It is used as a potentially useful NMDA receptor agonist. it is usually used as central nervous antitussive, cough suppressant. This is one of the most popular ingredients in over-the-counter cold and cough medications. Dextromethorphan hydrobromide may be added to other preparations to help treat </p>Formula:C18H26BrNOColor and Shape:White, Crystalline powderMolecular weight:352.32Dextromethorphan HBr
CAS:Formula:C18H25NO·HBrColor and Shape:White To Off-White SolidMolecular weight:271.40 80.91D-Methorphan hydrobromide
CAS:Controlled ProductFormula:C18H25NO·BrHColor and Shape:NeatMolecular weight:352.31Dextromethorphan hydrobromide
CAS:Controlled Product<p>Dextromethorphan hydrobromide is a drug that has been used to treat cough and cold symptoms. It is also an NMDA receptor antagonist, which blocks the activity of the NMDA receptor. Dextromethorphan hydrobromide is metabolized by the liver into dextrorphan and 3-methoxymorphinan, which are both active metabolites. Dextrorphan is a more potent NMDA receptor antagonist than dextromethorphan. The elimination half-life for dextrorphan is about 2 hours, whereas the elimination half-life for dextromethorphan is about 8 hours. The concentration–time curve for dextrorphan has been shown to be sigmoidal with a long tail, whereas the concentration–time curve for dextromethorphan has been shown to be linear with no long tail. Dextrorphan binds to adenosine A3 receptors in a competitive manner and has been shown</p>Formula:C18H25NO·HBrPurity:Min. 95%Molecular weight:352.31 g/mol
