CAS 125-71-3: Dextromethorphan
Description:Dextromethorphan (DXM) is a synthetic morphinan derivative primarily used as a cough suppressant in over-the-counter medications. It is classified as a non-opioid antitussive agent, meaning it alleviates coughing without the addictive properties associated with opioids. DXM acts on the central nervous system, specifically targeting the sigma-1 receptor and the NMDA receptor, which contributes to its cough-suppressing effects. The substance is typically administered in various formulations, including syrups, tablets, and lozenges. Dextromethorphan is generally well-tolerated, but it can cause side effects such as dizziness, nausea, and drowsiness. At higher doses, it may produce dissociative effects similar to those of hallucinogens, leading to its potential for misuse. The chemical structure of DXM includes a methoxy group, which distinguishes it from other morphinans. Its CAS number, 125-71-3, is a unique identifier used for regulatory and safety purposes. Overall, while DXM is effective for treating cough, it should be used responsibly to avoid adverse effects and potential misuse.
Formula:C18H25NO
InChI:InChI=1S/C18H25NO/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18/h6-7,12,15,17H,3-5,8-11H2,1-2H3/t15-,17+,18+/m1/s1
InChI key:InChIKey=MKXZASYAUGDDCJ-NJAFHUGGSA-N
SMILES:O(C1=CC=C2C(=C1)C34CCN(C)C(C2)C4CCCC3)C
- Synonyms:
- (+)-3-Methoxy-17-methylmorphinan
- (+)-3-methoxy-N-methylmorphinan
- (+)-cis-1,3,4,9,10,10a-hexahydro-6-methoxy-11-methyl-2H-10,4a-iminoethanophenanthrene
- (14Α)-3-Methoxy-17-Methylmorphinan
- (9α,13α,14α)-3-Methoxy-17-methylmorphinan
- 3-Methoxy-17-Methyl-(9Alpha,13Alpha,14Alpha)-Morphinan
- 3-Methoxy-17-methyl-9α,13α,14α-morphinan
- 9α,13α,14α-Morphinan, 3-methoxy-17-methyl-
- Ba 2666
- Benylin DM
- See more synonyms
- D-1,2,3,9,10,10a-Hexahydro-6-methoxy-11-methyl-4H-10,4a-iminoethanophenanthrene
- D-3-Methoxy-N-methylmorphinan
- DEX
- DXM
- DXM Free Base
- Dextromethorphane
- Dextrometorfano
- Morphinan, 3-methoxy-17-methyl-, (9α,13α,14α)-
- Nodex
- Romilar CF
- d-Methorphan
- Dextromethorphan
