CAS 125-72-4

Levorphanol tartrate

Description:

Levorphanol tartrate is an opioid analgesic that is primarily used for the management of moderate to severe pain. It is a stereoisomer of the morphinan class of compounds, specifically the levorphanol form, which is known for its potent analgesic properties. The tartrate salt form enhances its solubility and stability. Levorphanol acts on the central nervous system by binding to mu-opioid receptors, providing pain relief while also possessing antitussive and sedative effects. Its pharmacological profile includes a longer duration of action compared to some other opioids, making it suitable for chronic pain management. However, like other opioids, it carries a risk of dependence, tolerance, and potential for abuse. Common side effects may include dizziness, nausea, constipation, and respiratory depression. Due to its potency and potential for misuse, levorphanol tartrate is classified as a controlled substance in many jurisdictions, necessitating careful prescribing and monitoring by healthcare professionals.

Formula: C₂₁H₂₉NO₇

InChI: InChI=1/C17H23NO.C4H6O6/c1-18-9-8-17-7-3-2-4-14(17)16(18)10-12-5-6-13(19)11-15(12)17;5-1(3(7)8)2(6)4(9)10/h5-6,11,14,16,19H,2-4,7-10H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/t14-,16+,17+;/m0./s1

InChI key: InChIKey=RWTWIZDKEIWLKQ-IWWMGODWSA-N

SMILES: [C@@H]([C@H](C(O)=O)O)(C(O)=O)O.CN1[C@]2([C@]3([C@](C=4C(C2)=CC=C(O)C4)(CC1)CCCC3)[H])[H]

Synonyms:

• 17-Methylmorphinan-3-Ol 2,3-Dihydroxybutanedioate (Salt)
• 17-Methylmorphinan-3-Ol 2,3-Dihydroxybutanedioate Hydrate (1:1:2)
• 2H-10,4a-Iminoethanophenanthren-6-ol, 1,3,4,9,10,10a-hexahydro-11-methyl-, tartrate
• <span class="text-smallcaps">D</span>-(-)-Levorphanol tartrate
• Lemoran
• Levo-Dromoran
• Levorphan tartrate
• Levorphanol Tartrate
• Levorphanol bitartrate
• Morphinan-3-ol, 17-methyl-, (2R,3R)-2,3-dihydroxybutanedioate (1:1) (salt)
• Morphinan-3-ol, 17-methyl-, [R-(R*,R*)]-2,3-dihydroxybutanedioate (1:1) (salt)
• Morphinan-3-ol, 17-methyl-, tartrate (1:1) (salt)
• NSC 91012
• Nih 4590
• Ro 1-5431/7
• Tartaric acid, compd. with 1,3,4,9,10,10a-hexahydro-11-methyl-2H-10,4a-iminoethanophenanthren-6-ol
• l-3-Hydroxy-N-methylmorphinan bitartrate

Levorphanol Tartrate

Controlled Product

CAS: 125-72-4

Stability Hygroscopic
Applications Levorphanol Tartrate is an orally active synthetic morphine analog. Analgesic (narcotic). Controlled substance.
References Randall, L.O., et al.: J. Pharmacol. Exp. Ther., 99, 163 (1950), Dajani, E., et al.: Eur. J. Pharmacol., 34, 105 (1975), Winpenny, J., et al.: Drugs, 8, 416 (2005),

Formula: C₁₇H₂₃NO•C₄H₆O₆

Color and Shape: Neat

Molecular weight: 257.3715009

Ref: TR-L376500

Levorphanol L-Tartrate (1 mg/mL in Methanol)

Controlled Product

CAS: 125-72-4

Formula: C₁₇H₂₃NO•C₄H₆O₆

Color and Shape: Kit

Molecular weight: 257.3715009

Ref: TR-KIT8295

Levorphanol-d3 L-Tartrate

Controlled Product

CAS: 125-72-4, 77-07-6

Applications Orally active synthetic labelled morphine analog. Analgesic (narcotic). Controlled substance.
References Randall, L.O., et al.: J. Pharmacol. Exp. Ther., 99, 163 (1950), Dajani, E., et al.: Eur. J. Pharmacol., 34, 105 (1975), Winpenny, J., et al.: Drugs, 8, 416 (2005),

Formula: C₁₇D₃H₂₀NO·C₄H₆O₆

Color and Shape: Neat

Molecular weight: 410.476

Ref: TR-L376502

Levorphanol tartrate (in methanol aS A

Controlled Product

CAS: 125-72-4

Levorphanol tartrate is a potent analgesic that is used for the treatment of severe pain. It works by binding to opioid receptors in the central nervous system, which results in the inhibition of pain signals. Levorphanol tartrate has also been shown to have anticancer properties, as it induces apoptosis in cancer cells and inhibits tumor growth. Additionally, this drug has been found to have an inhibitory effect on chitinase activity, which may be useful in the treatment of inflammatory diseases such as asthma and arthritis. Levorphanol tartrate analogs have also been investigated for their potential as kinase inhibitors, with promising results in preclinical studies. This drug is available as a methanol solution and is excreted primarily in urine after administration.

Formula: C₂₁H₂₉NO₇

Purity: Min. 95%

Molecular weight: 407.5 g/mol

Ref: 3D-AAA12572