CAS 125-73-5

Dextrorphan

Description:

Dextrorphan is an organic compound classified as an opioid and is a metabolite of dextromethorphan, which is commonly used as a cough suppressant. It is known for its dissociative and antitussive properties. Dextrorphan acts primarily as an NMDA receptor antagonist, which contributes to its psychoactive effects. The substance is typically encountered as a white to off-white crystalline powder and is soluble in water and alcohol. Its chemical formula is C18H25NO, and it has a molecular weight of approximately 275.4 g/mol. Dextrorphan is not considered to have significant analgesic properties compared to other opioids, but it may exhibit some mild stimulant effects. Due to its psychoactive nature, it is important to use dextrorphan under medical supervision, as misuse can lead to adverse effects. Additionally, it is subject to regulatory controls in various jurisdictions, reflecting concerns about its potential for abuse and dependence.

Formula: C₁₇H₂₃NO

InChI: InChI=1S/C17H23NO/c1-18-9-8-17-7-3-2-4-14(17)16(18)10-12-5-6-13(19)11-15(12)17/h5-6,11,14,16,19H,2-4,7-10H2,1H3/t14-,16+,17+/m1/s1

InChI key: InChIKey=JAQUASYNZVUNQP-PVAVHDDUSA-N

SMILES: CN1[C@@]2([C@@]3([C@@](C=4C(C2)=CC=C(O)C4)(CC1)CCCC3)[H])[H]

Synonyms:

• (+)-3-hydroxy-N-methylmorphinan
• (+)-Dromoran
• (+)-N-Methylmorphinan-3-ol
• (13Alpha,14Alpha)-17-Methylmorphinan-3-Ol
• (9Alpha,13Alpha,14Alpha)-17-Methylmorphinan-3-Ol
• (9α,13α,14α)-17-Methylmorphinan-3-ol
• 9α,13α,14α-Morphinan-3-ol, 17-methyl-
• Morphinan-3-ol, 17-methyl-, (9α,13α,14α)-
• O-Demethyldextromethorphan
• Ro 1-6794
• d-Levorphanol
• dextro-Dromoran

Dextrorphan, 1mg/ml in Methanol

CAS: 125-73-5

Color and Shape: Single Solution

Ref: LP-DEX-1873-FB-1LM

Dextrorphan Hemitartrate (Dextromethorphan EP Impurity B Hemitartrate)

CAS: 125-73-5

Formula: C₁₇H₂₃NO·C₄H₆O₆

Color and Shape: Off-White Solid

Molecular weight: 2*257.38 150.09

Ref: 4Z-D-043

Dextrorphan (Dextromethorphan EP Impurity B)

CAS: 125-73-5

Formula: C₁₇H₂₃NO

Molecular weight: 257.38

Ref: 4Z-D-045

Dextrorphan

CAS: 125-73-5

Color and Shape: White To Off-White

Ref: LP-DEX-1873-FB-10

Dextrorphan

Controlled Product

CAS: 125-73-5

Dextrorphan is a chemical that is structurally related to the opioid dextromethorphan. It has been shown to act as a non-selective antagonist of opioid receptors, with an affinity for the mu and kappa receptors. Dextrorphan has also been shown to inhibit the transcriptional activity of response elements. The matrix effect is a phenomenon where the presence of substances in the extracellular matrix can interfere with drug transport through the membrane, which may result in a lower concentration of drugs reaching their target site. Dextrorphan may also act as a transporter or competitive inhibitor of drug transporters such as P-glycoprotein.

Formula: C₁₇H₂₃NO

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 257.37 g/mol

Ref: 3D-FD158174