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CAS 1250-85-7

:

(11β)-21-(Acetyloxy)-9-fluoro-11-hydroxypregna-1,4,16-triene-3,20-dione

Description:
The chemical substance known as (11β)-21-(Acetyloxy)-9-fluoro-11-hydroxypregna-1,4,16-triene-3,20-dione, with the CAS number 1250-85-7, is a synthetic corticosteroid. It exhibits anti-inflammatory and immunosuppressive properties, making it useful in various therapeutic applications, particularly in treating conditions such as asthma, allergies, and autoimmune disorders. The structure of this compound features a fluorine atom, which enhances its potency and metabolic stability compared to other corticosteroids. The presence of an acetyloxy group contributes to its solubility and bioavailability. This compound is typically administered in a controlled manner to minimize potential side effects, which can include weight gain, hypertension, and increased susceptibility to infections. Its pharmacological effects are primarily mediated through the glucocorticoid receptor, leading to alterations in gene expression that modulate inflammatory responses. Overall, this substance is a significant agent in the field of medicine, particularly in the management of inflammatory and allergic conditions.
Formula:C23H27FO5
InChI:InChI=1S/C23H27FO5/c1-13(25)29-12-19(27)18-7-6-16-17-5-4-14-10-15(26)8-9-22(14,3)23(17,24)20(28)11-21(16,18)2/h7-10,16-17,20,28H,4-6,11-12H2,1-3H3/t16-,17-,20-,21-,22-,23-/m0/s1
InChI key:InChIKey=YVPGZUWNVLRAKT-XYNXPQAZSA-N
SMILES:F[C@@]12[C@]3(C)C(CC[C@]1([C@]4([C@](C)(C[C@@H]2O)C(C(COC(C)=O)=O)=CC4)[H])[H])=CC(=O)C=C3
Synonyms:
  • (11Beta)-9-Fluoro-11-Hydroxy-3,20-Dioxopregna-1,4,16-Trien-21-Yl Acetate
  • (11β)-21-(Acetyloxy)-9-fluoro-11-hydroxypregna-1,4,16-triene-3,20-dione
  • 21-Acetoxy-9a-fluoro-11b-hydroxypregna-1,4,16-triene-3,20-dione
  • 9-Fluoro-11beta,21-dihydroxypregna-1,4,16-triene-3,20-dione 21-acetate
  • Pregna-1,4,16-triene-3,20-dione, 21-(acetyloxy)-9-fluoro-11-hydroxy-, (11β)-
  • Pregna-1,4,16-triene-3,20-dione, 9-fluoro-11β,21-dihydroxy-, 21-acetate
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Found 4 products.