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11α,17,21-trihydroxypregn-4-ene-3,20-dione 21-acetate

CAS 1250-97-1: 11α,17,21-trihydroxypregn-4-ene-3,20-dione 21-acetate

Description:11α,17,21-trihydroxypregn-4-ene-3,20-dione 21-acetate, commonly known as hydrocortisone acetate, is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties. It is characterized by its steroidal structure, which includes a pregnane backbone with hydroxyl groups at the 11α, 17, and 21 positions, and an acetate group at the 21 position. This compound is typically used in various pharmaceutical formulations, particularly in topical applications for treating skin conditions, as well as in systemic therapies for conditions like adrenal insufficiency. Its mechanism of action involves binding to glucocorticoid receptors, leading to modulation of gene expression and subsequent anti-inflammatory effects. Hydrocortisone acetate is known for its relatively low potency compared to other corticosteroids, making it suitable for conditions requiring mild to moderate anti-inflammatory treatment. Additionally, it is soluble in organic solvents and has a relatively low solubility in water, which influences its formulation and delivery methods in clinical settings.

Formula:C23H32O6

InChI:InChI=1S/C23H32O6/c1-13(24)29-12-19(27)23(28)9-7-17-16-5-4-14-10-15(25)6-8-21(14,2)20(16)18(26)11-22(17,23)3/h10,16-18,20,26,28H,4-9,11-12H2,1-3H3/t16-,17-,18+,20+,21-,22-,23-/m0/s1

InChI key:InChIKey=ALEXXDVDDISNDU-VVCDUNCFSA-N

SMILES:O=C(OCC(=O)C1(O)CCC2C3CCC4=CC(=O)CCC4(C)C3C(O)CC21C)C

  • Synonyms:
  • (11Alpha)-11,17-Dihydroxy-3,20-Dioxopregn-4-En-21-Yl Acetate
  • (11α)-21-(Acetyloxy)-11,17-dihydroxypregn-4-ene-3,20-dione
  • 11-Epihydrocortisone Acetate
  • 21-Acetoxy-11α,17-dihydroxypregn-4-ene-3,20-dione
  • Epihydrocortisone 21-acetate
  • Pregn-4-ene-3,20-dione, 11α,17,21-trihydroxy-, 21-acetate
  • Pregn-4-ene-3,20-dione, 21-(acetyloxy)-11,17-dihydroxy-, (11α)-
  • Progesterone, 11α,17,21-trihydroxy-, 21-acetate
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Ref: 4Z-C-2749

5mg443.00 €
10mg749.00 €
25mg1,237.00 €
50mg2,148.00 €
100mg3,385.00 €
Estimated delivery in United States, on Tuesday 25 Mar 2025
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Epi Hydrocortisone 21-Acetate

Controlled Product
CAS:1250-97-1

Ref: TR-E587500

10mg208.00 €
25mg432.00 €
50mg772.00 €
Estimated delivery in United States, on Thursday 3 Apr 2025
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Epi hydrocortisone 21-acetate

Controlled Product
CAS:1250-97-1

Ref: 3D-FE22707

2mg145.00 €
5mg212.00 €
Estimated delivery in United States, on Friday 4 Apr 2025
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