CAS 1250-97-1

11α,17,21-trihydroxypregn-4-ene-3,20-dione 21-acetate

Description:

11α,17,21-trihydroxypregn-4-ene-3,20-dione 21-acetate, commonly known as hydrocortisone acetate, is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties. It is characterized by its steroidal structure, which includes a pregnane backbone with hydroxyl groups at the 11α, 17, and 21 positions, and an acetate group at the 21 position. This compound is typically used in various pharmaceutical formulations, particularly in topical applications for treating skin conditions, as well as in systemic therapies for conditions like adrenal insufficiency. Its mechanism of action involves binding to glucocorticoid receptors, leading to modulation of gene expression and subsequent anti-inflammatory effects. Hydrocortisone acetate is known for its relatively low potency compared to other corticosteroids, making it suitable for conditions requiring mild to moderate anti-inflammatory treatment. Additionally, it is soluble in organic solvents and has a relatively low solubility in water, which influences its formulation and delivery methods in clinical settings.

Formula: C₂₃H₃₂O₆

InChI: InChI=1/C23H32O6/c1-13(24)29-12-19(27)23(28)9-7-17-16-5-4-14-10-15(25)6-8-21(14,2)20(16)18(26)11-22(17,23)3/h10,16-18,20,26,28H,4-9,11-12H2,1-3H3/t16-,17-,18+,20+,21-,22-,23-/m0/s1

InChI key: InChIKey=ALEXXDVDDISNDU-VVCDUNCFSA-N

SMILES: C[C@@]12[C@]([C@]3([C@]([C@H](O)C1)([C@]4(C)C(CC3)=CC(=O)CC4)[H])[H])(CC[C@@]2(C(COC(C)=O)=O)O)[H]

Synonyms:

• (11Alpha)-11,17-Dihydroxy-3,20-Dioxopregn-4-En-21-Yl Acetate
• (11α)-21-(Acetyloxy)-11,17-dihydroxypregn-4-ene-3,20-dione
• 11-Epihydrocortisone Acetate
• 21-Acetoxy-11α,17-dihydroxypregn-4-ene-3,20-dione
• Epihydrocortisone 21-acetate
• Pregn-4-ene-3,20-dione, 11α,17,21-trihydroxy-, 21-acetate
• Pregn-4-ene-3,20-dione, 21-(acetyloxy)-11,17-dihydroxy-, (11α)-
• Progesterone, 11α,17,21-trihydroxy-, 21-acetate

Epi Hydrocortisone 21-Acetate

CAS: 1250-97-1

Formula: C₂₃H₃₂O₆

Molecular weight: 404.51

Ref: 4Z-H-103040

Epi Hydrocortisone 21-Acetate

Controlled Product

CAS: 1250-97-1

Applications Epi Hydrocortisone 21-Acetate is an analog of Hydrocortisone (H714620), which is a glucocorticoid.
References Toscano, L., et al.: J. Med. Chem., 20, 213 (1977), Middleton, B., et al.: J. Biol. Chem., 256, 4827 (1981), Moore, A., et al.: Ann. Clin. Biochem., 22, 435 (1985)

Formula: C₂₃H₃₂O₆

Color and Shape: Neat

Molecular weight: 404.50

Ref: TR-E587500

Epi hydrocortisone 21-acetate

Controlled Product

CAS: 1250-97-1

Epi hydrocortisone 21-acetate is a high quality chemical. It is a reagent, which is used as a fine chemical, useful scaffold, and versatile building block in synthetic chemistry. Epi hydrocortisone 21-acetate has CAS No. 1250-97-1 and can be used in research chemicals or speciality chemicals. This compound is also a reaction component that can be used to synthesize other compounds with desirable properties.

Formula: C₂₃H₃₂O₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 404.5 g/mol

Ref: 3D-FE22707

Hydrocortisone Acetate EP Impurity F

CAS: 1250-97-1

Formula: C₂₃H₃₂O₆

Molecular weight: 404.5

Ref: ST-EA-CP-H9025