CAS 125093-93-8

(lys1,pro2,5,arg3,4,tyr6)-vasoactive*intestinal P

Description:

The chemical substance known as (lys1,pro2,5,arg3,4,tyr6)-vasoactive intestinal peptide (VIP) is a neuropeptide that plays a crucial role in various physiological processes. It is composed of a sequence of amino acids, including lysine, proline, arginine, and tyrosine, which contribute to its biological activity. VIP is primarily involved in the regulation of smooth muscle relaxation, vasodilation, and the stimulation of glandular secretion, particularly in the gastrointestinal tract. It also has neuroprotective effects and is implicated in neurotransmission within the central nervous system. The peptide exhibits a high degree of specificity for its receptors, which are part of the G protein-coupled receptor family. Its therapeutic potential is being explored in conditions such as asthma, inflammatory bowel disease, and other disorders related to the nervous and digestive systems. The CAS number 125093-93-8 uniquely identifies this compound, facilitating its recognition in scientific literature and databases. Overall, VIP is a significant molecule in both physiological and pathological contexts.

Formula: C₁₅₄H₂₅₇N₄₉O₄₀S

Synonyms:

• VIP Antagonist
• H-Lys-Pro-Arg-Arg-Pro-Tyr-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2

VIP Antagonist

CAS: 125093-93-8

VIP antagonist, a hybrid of neurotensin (6-11) and VIP (7-28), is a competitive antagonist of VIP-binding to glial cells. In rats with reduced masculine potential, The peptide markedly inhibits VIP-stimulated sexual behaviour. Furthermore, it has been shown to antagonize VIP receptors on non-small cell lung cancer cells, thereby inhibiting tumor growth in vitro and in vivo.

Formula: C₁₅₄H₂₅₇N₄₉O₄₀S

Purity: 95.3%

Color and Shape: White

Molecular weight: 3467.11

Ref: 01-4031352

VIP Antagonist

CAS: 125093-93-8

VIP Antagonist is a drug that inhibits the α7 nicotinic acetylcholine receptor and has been shown to have inhibitory properties against cancer tissues. The drug blocks the response element for VIP, inhibiting cyclase activity. This prevents the production of VIP and other neuropeptides, which are involved in nerve cell growth and survival. VIP Antagonist also inhibits toll-like receptor signaling pathways by blocking TLR2 and TLR4, which are receptors on immune cells that recognize bacterial products. In addition, this drug binds to human immunoglobulin G (IgG) and prevents it from binding to its Fc receptor on immune cells, thus preventing IgG-mediated complement activation or antibody-dependent cellular cytotoxicity.

Formula: C₁₅₄H₂₅₇N₄₉O₄₀S

Purity: Min. 95%

Molecular weight: 3,467.06 g/mol

Ref: 3D-PVA-3757-PI

VIP Antagonist

CAS: 125093-93-8

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Formula: C₁₅₄H₂₅₇N₄₉O₄₀S

Molecular weight: 3,467.13 g/mol

Ref: 3D-PP50098

VIP Antagonist

CAS: 125093-93-8

The VIP antagonist is a model system that has been shown to inhibit the activity of VIP in fetal bovine lung. The VIP antagonist has been shown to be effective against a variety of cancers, including colon cancer and prostate cancer. It also inhibits the production of cytosolic Ca2+ in human skin cells and has anti-inflammatory properties. The VIP antagonist's biological properties have been studied extensively, including its ability to induce neuronal death by inhibiting the release of neurotransmitters from neurons in culture.

Formula: C₁₅₄H₂₅₇N₄₉O₄₀S

Purity: Min. 95%

Molecular weight: 3,467.06 g/mol

Ref: 3D-FV110467