CAS 1251156-08-7
:XL388
Description:
XL388, with the CAS number 1251156-08-7, is a chemical compound that functions primarily as a selective inhibitor of the mTOR (mechanistic target of rapamycin) pathway. This pathway plays a crucial role in regulating cell growth, proliferation, and survival, making XL388 of interest in cancer research and potential therapeutic applications. The compound is characterized by its ability to interfere with the signaling mechanisms that promote tumor growth, thereby offering a targeted approach to cancer treatment. In addition to its antitumor properties, XL388 may also exhibit effects on metabolic processes and immune responses. Its pharmacological profile includes considerations of bioavailability, solubility, and toxicity, which are essential for evaluating its efficacy and safety in clinical settings. As with many investigational drugs, ongoing research is necessary to fully understand its mechanisms of action, potential side effects, and therapeutic windows. Overall, XL388 represents a promising candidate in the field of oncology and targeted therapies.
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Found 5 products.
XL388
CAS:XL388 is a highly effective, specifc, ATP-competitive inhibitor of mTOR ( IC50: 9.9 nM), 1000-fold selectivity than the closely related PI3K kinases.Formula:C23H22FN3O4SPurity:99.39% - 99.53%Color and Shape:SolidMolecular weight:455.5XL388
CAS:Controlled Product<p>Applications XL388 is a highly potent, orally bioavailable, selective, ATP-competitive mammalian target of rapamycin (mTOR) inhibitor. XL388 has shown significant and dose-dependent antitumor activity in athymic nude mice implanted with human tumor xenografts.<br>References Takeuchi, C.S., et. al.: J Med. Chem., 56, 2218 (2013)<br></p>Formula:C23H22FN3O4SColor and Shape:NeatMolecular weight:455.50
