CAS 1251537-19-5

(5S,8E,10E,12R)-12-[[(1,1-Dimethylethyl)diphenylsilyl]oxy]-5-hydroxy-15-(trimethylsilyl)-8,10-Pentadecadiene-6,14-diynoic acid 1-Methylethyl Ester

Controlled Product

CAS: 1251537-19-5

Applications (5S,8E,10E,12R)-12-[[(1,1-Dimethylethyl)diphenylsilyl]oxy]-5-hydroxy-15-(trimethylsilyl)-8,10-Pentadecadiene-6,14-diynoic acid 1-Methylethyl Ester is an intermediate in the synthesis of Resolvin E1 (R144690), an omega-3 polyunsaturated fatty acid derivative that exhibits potent anti-inflammatory, pro-resolution, and anti-nociceptive effects.
References Allard, M., et al.: Tetrahedron. Lett., 52, 2623 (2011); Allard, M., et al.: Tetrahedron. Lett., 52, 6512 (2011);

Formula: C₂₁H₂₅FN₄O₈

Color and Shape: Neat

Molecular weight: 480.444

Ref: TR-D461535