CAS 1251578-67-2

N-(4-Fluorophenyl)-6-morpholino-9H-purin-2-amine

Description:

N-(4-Fluorophenyl)-6-morpholino-9H-purin-2-amine, with the CAS number 1251578-67-2, is a chemical compound that belongs to the purine class of molecules. It features a purine core, which is a bicyclic structure composed of fused imidazole and pyrimidine rings, substituted with a morpholino group and a fluorophenyl moiety. The presence of the 4-fluorophenyl group introduces a fluorine atom, which can enhance the compound's biological activity and lipophilicity. The morpholino group contributes to the compound's solubility and may influence its pharmacokinetic properties. This compound is of interest in medicinal chemistry, particularly in the development of pharmaceuticals targeting various biological pathways, including those involved in cancer and viral infections. Its specific interactions with biological targets, such as enzymes or receptors, would depend on its three-dimensional conformation and electronic properties, which are influenced by the substituents on the purine ring. Overall, N-(4-Fluorophenyl)-6-morpholino-9H-purin-2-amine exemplifies the complexity and potential of modified purine derivatives in drug design.

Formula: C₁₅H₁₅FN₆O

Synonyms:

• N-(4-Fluorophenyl)-6-morpholino-9H-purin-2-amine
• Topoisomerase
• 9H-Purin-2-amine, N-(4-fluorophenyl)-6-(4-morpholinyl)-

N-(4-Fluorophenyl)-6-(morpholin-4-yl)-9H-purin-2-amine

CAS: 1251578-67-2

Versatile small molecule scaffold

Formula: C₁₅H₁₅FN₆O

Purity: Min. 95%

Molecular weight: 314.32 g/mol

Ref: 3D-BAC57867

Topoisomerase IIα-IN-8

CAS: 1251578-67-2

Topoisomerase IIα-IN-8 (compound 15) serves as a modest inhibitor of human DNA topoisomerase IIα (htIIα), exhibiting an inhibitory concentration (IC50) of 462 ± 38.0 μM [1].

Formula: C₁₅H₁₅FN₆O

Color and Shape: Solid

Molecular weight: 314.324

Ref: TM-T84739