CAS 1252018-10-2

4-[4-(N-(3-chloro-(2R)-2-hydroxy-1-propyl)amino)phenyl]morpholin-3-one

Description:

4-[4-(N-(3-chloro-(2R)-2-hydroxy-1-propyl)amino)phenyl]morpholin-3-one, identified by its CAS number 1252018-10-2, is a chemical compound characterized by its complex structure, which includes a morpholine ring and a chloro-substituted propyl group. This compound features a phenyl group that is substituted with an amino group, which is further linked to a chloro-hydroxy propyl moiety. The presence of the morpholine ring contributes to its potential biological activity, as morpholines are often found in pharmacologically active compounds. The chloro and hydroxy groups may influence the compound's solubility and reactivity, while the amino group can participate in hydrogen bonding and other interactions. Overall, this compound may exhibit properties relevant to medicinal chemistry, particularly in the development of therapeutic agents, although specific biological activities would require further investigation through experimental studies. Its structural complexity suggests potential applications in various fields, including pharmaceuticals and agrochemicals.

Formula: C₁₃H₁₇ClN₂O₃

Synonyms:

• 4-[4-(N-(3-chloro-(2R)-2-hydroxy-1-propyl)aMino)phenyl]Morpholin-3-one
• 4-[4-(N-(3-chloro-(2R)-2-hydroxy-1-p ropyl)amino)phenyl]morpholin-3-one 2-[(2R)-2-hydroxy-3-{[4-(3-oxomorph olin-4-yl)phenyl]amino}propyl]-1H-is oindole-1,3(2H)-dione 2-[[(5S)-2-Oxo-3-[4-(3-oxo-4-morpho linyl)phenyl]-5-oxazolidinyl]methyl]-1H-isoindole-1
• (R)-4-[4-[(3-Chloro-2-hydroxypropyl)amino]phenyl]morpholin-3-one

Rivaroxaban Impurity 111

CAS: 1252018-10-2

Formula: C₁₃H₁₇ClN₂O₃

Color and Shape: White To Off-White Solid

Molecular weight: 284.74

Ref: 4Z-R-2966

4-[4-[[(2R)-3-Chloro-2-hydroxypropyl]amino]phenyl]-3-morpholinone

Controlled Product

CAS: 1252018-10-2

Impurity Rivaroxaban Impurity E
Applications 4-[4-[[(2R)-3-Chloro-2-hydroxypropyl]amino]phenyl]-3-morpholinone (Rivaroxaban Impurity E) is an impurity of Rivaroxaban (R538000), which is a antithrombotic agent and a FXa inhibitor.
References Ansell, J., et al.: Drugs, 64, 1 (2004), Eriksson, B., et al.: J. Thromb. Haemost., 3, 103 (2005), Kubitza, D., et al.: Clin. Pharmacol. Ther., 78, 412 (2005),

Formula: C₁₃H₁₇ClN₂O₃

Color and Shape: Neat

Molecular weight: 284.74

Ref: TR-C292820

Rivaroxaban impurity E

CAS: 1252018-10-2

Formula: C₁₃H₁₇ClN₂O₃

Molecular weight: 284.74

Ref: ST-EA-CP-R17039