CAS 125238-99-5

Fmoc-Dab(Boc)-OH

Description:

Fmoc-Dab(Boc)-OH, also known as Fmoc-2,3-diaminobutyric acid (Boc), is a protected amino acid commonly used in peptide synthesis. The "Fmoc" (9-fluorenylmethoxycarbonyl) group serves as a protective group for the amino functionality, allowing for selective reactions without interfering with other functional groups. The "Boc" (tert-butyloxycarbonyl) group protects the amine side chain, providing stability during synthesis. This compound is characterized by its ability to facilitate the formation of peptide bonds while maintaining the integrity of the amino acid's functional groups. It is typically used in solid-phase peptide synthesis due to its compatibility with various coupling reagents and its ease of removal under mild acidic conditions. Fmoc-Dab(Boc)-OH is soluble in organic solvents like dimethylformamide (DMF) and dichloromethane, making it suitable for various synthetic protocols. Its structural features contribute to the development of peptides with specific biological activities, making it valuable in pharmaceutical and biochemical research.

Formula: C₂₄H₂₈N₂O₆

InChI: InChI=1/C24H28N2O6/c1-24(2,3)32-22(29)25-13-12-20(21(27)28)26-23(30)31-14-19-17-10-6-4-8-15(17)16-9-5-7-11-18(16)19/h4-11,19-20H,12-14H2,1-3H3,(H,25,29)(H,26,30)(H,27,28)/t20-/m0/s1

InChI key: LIWKOFAHRLBNMG-FQEVSTJZSA-N

SMILES: CC(C)(C)OC(=NCC[C@@H](C(=O)O)N=C(O)OCC1c2ccccc2c2ccccc12)O

Synonyms:

• Fmoc-Dbu(Boc)-OH
• Fmoc-4-Boc-L-2,4-diaminobutyric acid
• Fmoc-L-2,4-Diaminobutyric acid(Boc)
• Fmoc-Dab(Boc)
• (2S)-4-[(tert-butoxycarbonyl)amino]-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}butanoic acid
• Fmoc-L-Dab(Boc)-OH

(S)-4-(Boc-amino)-2-(Fmoc-amino)butyric acid, 96%

CAS: 125238-99-5

It finds its application in combination with the N-Z derivative for the synthesis of polymyxin analogs. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Ae

Formula: C₂₄H₂₈N₂O₆

Purity: 96%

Molecular weight: 440.5

Ref: 02-H51990

Fmoc-Dab(Boc)-OH

CAS: 125238-99-5

Used in combination with the Nγ-Z derivative for the synthesis of polymyxin analogs.

Formula: C₂₄H₂₈N₂O₆

Purity: 99.7%

Color and Shape: White

Molecular weight: 440.5

Ref: 01-4016009

(2S)-2,4-Diaminobutanoic acid, 4-BOC, 2-FMOC protected

CAS: 125238-99-5

(2S)-2,4-Diaminobutanoic acid, 4-BOC, 2-FMOC protected

Formula: C₂₄H₂₈N₂O₆

Purity: 97%

Color and Shape: White Solid-Powder

Molecular weight: 440.48891

Ref: 54-OR14669

Fmoc-Dab(Boc)-OH

CAS: 125238-99-5

Formula: C₂₄H₂₈N₂O₆

Purity: ≥ 98.0%

Color and Shape: White powder

Molecular weight: 440.50

Ref: 7W-GM1659

Fmoc-Dab(Boc)-OH

CAS: 125238-99-5

Formula: C₂₄H₂₈N₂O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 440.4889

Ref: IN-DA000ND6

Fmoc-Dab(Boc)-OH

CAS: 125238-99-5

Fmoc-Dab(Boc)-OH is a chemical intermediate used for chemical synthesis.

Formula: C₂₄H₂₈N₂O₆

Color and Shape: Solid

Molecular weight: 440.4889

Ref: TM-T21353

Fmoc-Dab(Boc)-OH

CAS: 125238-99-5

Fmoc-Dab(Boc)-OH

Formula: C₂₄H₂₈N₂O₆

Purity: 97%

Molecular weight: 440.49

Ref: IN-DG31677

Fmoc-Dab(Boc)-OH

CAS: 125238-99-5

Fmoc-Dab(Boc)-OH is a fatty acid that is conjugated to an amino acid. It has been shown to have binding activity against activated, solid-phase synthesis, and synthetic compounds. Fmoc-Dab(Boc)-OH is a cyclic lipopeptide with antimicrobial properties. It has been shown to be active against resistant microorganisms such as Enterococcus faecalis and Pseudomonas aeruginosa. This molecule has also been shown to have pro-inflammatory cytokine activity in human colon carcinoma cells, which may lead to the suppression of tumor growth.

Formula: C₂₄H₂₈N₂O₆

Purity: Min. 95 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 440.49 g/mol

Ref: 3D-FF33013

Fmoc-N4-Boc- L-2,4-diaminobutyric acid

CAS: 125238-99-5

Formula: C₂₄H₂₈N₂O₆

Purity: 95%

Color and Shape: Solid

Molecular weight: 440.496

Ref: 10-F093524

Fmoc-Dab(Boc)-OH

Controlled Product

CAS: 125238-99-5

Applications Fmoc-Dab(Boc)-OH,

Formula: C₂₄H₂₆N₂O₆

Color and Shape: Neat

Molecular weight: 440.49

Ref: TR-F628608