CAS 1252637-46-9

2-Pyrrolidinecarboxamide, N-(1-cyanocyclopropyl)-4-[[4-(2-methyl-4-pyridinyl)-2-(trifluoromethyl)phenyl]sulfonyl]-1-[[1-(trifluoromethyl)cyclopropyl]carbonyl]-, (2S,4R)-

Description:

2-Pyrrolidinecarboxamide, N-(1-cyanocyclopropyl)-4-[[4-(2-methyl-4-pyridinyl)-2-(trifluoromethyl)phenyl]sulfonyl]-1-[[1-(trifluoromethyl)cyclopropyl]carbonyl]-, (2S,4R)-, identified by CAS number 1252637-46-9, is a synthetic organic compound characterized by its complex molecular structure, which includes multiple functional groups such as amides, sulfonyl, and trifluoromethyl groups. This compound is likely to exhibit significant biological activity, making it of interest in pharmaceutical research, particularly in the development of therapeutics. Its stereochemistry, indicated by the (2S,4R) designation, suggests specific spatial arrangements of atoms that can influence its interaction with biological targets. The presence of the cyanocyclopropyl and trifluoromethyl groups may enhance its lipophilicity and metabolic stability. Additionally, the compound's solubility, stability, and reactivity can be influenced by these substituents, which are critical for its potential applications in medicinal chemistry. Overall, this compound represents a unique structure that may contribute to its efficacy in various biological contexts.

Formula: C₂₇H₂₄F₆N₄O₄S

Synonyms:

• 2-Pyrrolidinecarboxamide, N-(1-cyanocyclopropyl)-4-[[4-(2-methyl-4-pyridinyl)-2-(trifluoromethyl)phenyl]sulfonyl]-1-[[1-(trifluoromethyl)cyclopropyl]carbonyl]-, (2S,4R)-
• RO5461111

RO5461111

CAS: 1252637-46-9

RO5461111: Oral Cathepsin S inhibitor, IC50 of 0.4 nM (human) & 0.5 nM (mouse), reduces T/B cell activation, treats lung inflammation & lupus nephritis.

Formula: C₂₇H₂₄F₆N₄O₄S

Color and Shape: Solid

Molecular weight: 614.56

Ref: TM-T73220