CAS 1253-84-5
:Cholestane-3β,5α,6β-triol
Description:
Cholestane-3β,5α,6β-triol is a steroid alcohol, specifically a triol, characterized by the presence of three hydroxyl (-OH) groups. It is derived from cholesterol and features a tetracyclic structure typical of steroids, with specific stereochemistry at the 3β, 5α, and 6β positions. This compound is typically solid at room temperature and is insoluble in water but soluble in organic solvents, reflecting its hydrophobic nature. Cholestane-3β,5α,6β-triol plays a role in various biological processes, including cell membrane structure and function, and may be involved in signaling pathways. Its hydroxyl groups contribute to its reactivity and potential interactions with other biomolecules. The compound is of interest in biochemical research, particularly in studies related to lipid metabolism and steroid biochemistry. Safety data indicates that, like many steroid compounds, it should be handled with care, as it may have biological effects that require further investigation.
Formula:C27H48O3
InChI:InChI=1S/C27H48O3/c1-17(2)7-6-8-18(3)21-9-10-22-20-15-24(29)27(30)16-19(28)11-14-26(27,5)23(20)12-13-25(21,22)4/h17-24,28-30H,6-16H2,1-5H3/t18-,19+,20+,21-,22+,23+,24-,25-,26-,27+/m1/s1
InChI key:InChIKey=YMMFNKXZULYSOQ-RUXQDQFYSA-N
SMILES:C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@]([C@@H](CCCC(C)C)C)(CC4)[H])[H])(C[C@@H](O)[C@@]1(O)C[C@@H](O)CC2)[H])[H]
Synonyms:- (3Beta,5Alpha,6Beta)-Cholestane-3,5,6-Triol
- (3Beta,5Alpha,6Beta,8Xi,9Xi,14Xi,17Xi,20Xi)-Cholestane-3,5,6-Triol
- (3β,5α,6β)-Cholestane-3,5,6-triol
- 3β,5α,6β-Trihydroxycholestane
- 3β-Hydroxycholestane-5α,6β-diol
- 5-Alpha-Cholestane-3-Beta,5,6-Beta-Triol
- 5α,6β-Dihydroxycholestanol
- 5α-Cholestane-3β,5,6β-triol
- Cholesta-3β,5α,6β-triol
- Cholestane-3,5,6-triol
- Cholestane-3,5,6-triol, (3β,5α,6β)-
- Cholestanetriol
- NSC 124751
- NSC 18178
- See more synonyms
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Found 9 products.
(3S,5R,6R,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-17-((R)-6-methylheptan-2-yl)hexadecahydro-1H-cyclopenta[a]phenanthrene-3,5,6-triol
CAS:Formula:C27H48O3Purity:95%Color and Shape:SolidMolecular weight:420.66825α,6β-Dihydroxycholestanol
CAS:Formula:C27H48O3Purity:>95%Color and Shape:SolidMolecular weight:420.673β,5α,6β-Trihydroxycholestane
CAS:<p>3β,5α,6β-Trihydroxycholestane is a cholesterol metabolite found mainly in animal fats, and modulates SMO activity.</p>Formula:C27H48O3Purity:97% - 99.78%Color and Shape:SolidMolecular weight:420.673b,5a,6b-Trihydroxycholestane
CAS:<p>Applications Cholesterol analog. Useful for treatment of hyperlipemia, arteriosclerosis, diabetes, obesity.<br>References Watson, K., et al.: J. Clin. Invest., 93, 2106 (1994), Wada, T., et al.: Circ. Res., 84, 166 (1999), Engelse, M., et al.: Cardiovasc. Res., 52, 281 (2001), Landis, M., et al.: J. Biol. Chem., 277, 4713 (2002),<br></p>Formula:C27H48O3Color and Shape:NeatMolecular weight:420.67Cholestan-3β,5α,6β-triol
CAS:Controlled Product<p>Cholestan-3b,5a,6b-triol is a naturally occurring fatty acid that has been shown to inhibit the synthesis of cholesterol and oxysterols in animal studies. It also acts as a receptor agonist for the LDL receptor. This compound is used in clinical trials to assess risk for cerebrotendinous xanthomatosis (CTX), a rare genetic disorder characterized by high levels of cholesterol and fatty acids in the brain and spinal cord. Cholestan-3b,5a,6b-triol is being studied as a potential treatment for atherosclerosis. The drug inhibits the uptake of cholesterol from macrophages and reduces the accumulation of atherosclerotic lesions in mouse models. Cholestan-3b,5a,6b-triol may be useful for treating patients with diabetes because it blocks the synthesis of fatty acids that can lead to diabetic complications such as retinopathy and nephropathy.</p>Formula:C27H48O3Purity:Min. 95%Color and Shape:PowderMolecular weight:420.67 g/mol
