CAS 125316-60-1: AHPN

Description: AHPN, or 2-Amino-3-hydroxy-5-phenyl-1H-pyrrole-4-carbonitrile, is a chemical compound characterized by its unique pyrrole structure, which includes an amino group, a hydroxyl group, and a phenyl substituent. This compound is known for its potential applications in medicinal chemistry, particularly in the development of pharmaceuticals due to its bioactive properties. AHPN may exhibit various biological activities, including anti-inflammatory and anti-cancer effects, making it a subject of interest in research. The presence of the carbonitrile group contributes to its reactivity and potential for further chemical modifications. AHPN is typically synthesized through multi-step organic reactions, and its properties can be influenced by factors such as pH and solvent conditions. As with many organic compounds, safety data should be consulted to understand its handling and toxicity. Overall, AHPN represents a class of compounds that bridge organic chemistry and pharmacology, highlighting the importance of structure-activity relationships in drug design.

Formula: C₂₇H₂₆O₃

InChI: InChI=1S/C27H26O3/c28-25-6-5-22(20-1-2-21-11-23(26(29)30)4-3-19(21)10-20)12-24(25)27-13-16-7-17(14-27)9-18(8-16)15-27/h1-6,10-12,16-18,28H,7-9,13-15H2,(H,29,30)

InChI key: InChIKey=LDGIHZJOIQSHPB-UHFFFAOYSA-N

SMILES: O=C(O)C=1C=CC2=CC(=CC=C2C1)C=3C=CC(O)=C(C3)C45CC6CC(CC(C6)C4)C5

Synonyms:

• 2-Naphthalenecarboxylic acid, 6-(4-hydroxy-3-tricyclo[3.3.1.1^3,7]dec-1-ylphenyl)-
• 2-Naphthalenecarboxylicacid,6-(4-Hydroxy-3-Tricyclo(3.3.1.1(3,7))Dec-1-Ylphen
• 6-(4-Hydroxy-3-Tricyclo(3.3.1.1(3,7))Dec-1-Ylphenyl)-2-Naphthalenecarboxylic
• 6-(4-Hydroxy-3-tricyclo[3.3.1.1^3,7]dec-1-ylphenyl)-2-naphthalenecarboxylic acid
• 6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthalenecarboxylic acid
• 6-[4-Hydroxy-3-(Tricyclo[3.3.1.1~3,7~]Dec-1-Yl)Phenyl]Naphthalene-2-Carboxylic Acid
• AHPN, 6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid
• C 5865
• Cd 437
• Cd 437/Ahpn
• 2-Naphthalenecarboxylic acid, 6-(4-hydroxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)-
• 6-(4-Hydroxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)-2-naphthalenecarboxylic acid
• AHPN

2-Naphthalenecarboxylic acid, 6-(4-hydroxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)-

CAS: 125316-60-1

• Formula: C₂₇H₂₆O₃
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 398.4935

CD437

CAS: 125316-60-1

• Formula: C₂₇H₂₆O₃
• Molecular weight: 398.49

O-Desmethyl Adapalene

CAS: 125316-60-1

• Formula: C₂₇H₂₆O₃
• Color and Shape: Off-White Solid
• Molecular weight: 398.51

CD437

CAS: 125316-60-1

• Purity: 99.62%
• Molecular weight: 398.49g/mol

6-[3-(1-Adamantyl)-4-Hydroxyphenyl]Naphthalene-2-Carboxylic Acid

CAS: 125316-60-1

• Purity: 98%
• Molecular weight: 398.49g/mol

O-Desmethyl Adapalene-13C6

CAS: 125316-60-1

• Formula: C₂₁₁₃C₆H₂₆O₃
• Color and Shape: White To Off-White Solid
• Molecular weight: 404.46

CD 437

CAS: 125316-60-1

• Formula: C₂₇H₂₆O₃
• Purity: >93.0%(qNMR)
• Color and Shape: White to Light gray to Light yellow powder to crystal
• Molecular weight: 398.50

CD437

CAS: 125316-60-1

CD437 (AHPN) is a specifc Retinoic Acid Receptor γ (RARγ) agonist.

• Formula: C₂₇H₂₆O₃
• Purity: 98.79% - 99.63%
• Color and Shape: Solid
• Molecular weight: 398.49

O-Desmethyl Adapalene

CAS: 125316-60-1

Applications An intermediate in the preparation of Adapalene derivatives. References Zinner, R., et al.: Mol. …

• Formula: C₂₇H₂₆O₃
• Color and Shape: Neat
• Molecular weight: 398.49

O-Desmethyl adapalene

CAS: 125316-60-1

Adapalene is a synthetic retinoid that acts as an agonist for the RAR-β2 receptor and …

• Formula: C₂₇H₂₆O₃
• Purity: Min. 95%
• Molecular weight: 398.49 g/mol