CAS 125316-60-1

AHPN

Description:

AHPN, or 2-Amino-3-hydroxy-5-phenyl-1H-pyrrole-4-carbonitrile, is a chemical compound characterized by its unique pyrrole structure, which includes an amino group, a hydroxyl group, and a phenyl substituent. This compound is known for its potential applications in medicinal chemistry, particularly in the development of pharmaceuticals due to its bioactive properties. AHPN may exhibit various biological activities, including anti-inflammatory and anti-cancer effects, making it a subject of interest in research. The presence of the carbonitrile group contributes to its reactivity and potential for further chemical modifications. AHPN is typically synthesized through multi-step organic reactions, and its properties can be influenced by factors such as pH and solvent conditions. As with many organic compounds, safety data should be consulted to understand its handling and toxicity. Overall, AHPN represents a class of compounds that bridge organic chemistry and pharmacology, highlighting the importance of structure-activity relationships in drug design.

Formula: C₂₇H₂₆O₃

InChI: InChI=1S/C27H26O3/c28-25-6-5-22(20-1-2-21-11-23(26(29)30)4-3-19(21)10-20)12-24(25)27-13-16-7-17(14-27)9-18(8-16)15-27/h1-6,10-12,16-18,28H,7-9,13-15H2,(H,29,30)

InChI key: InChIKey=LDGIHZJOIQSHPB-UHFFFAOYSA-N

SMILES: OC=1C(C23CC4CC(C2)CC(C3)C4)=CC(=CC1)C5=CC6=C(C=C5)C=C(C(O)=O)C=C6

Synonyms:

• 2-Naphthalenecarboxylic acid, 6-(4-hydroxy-3-tricyclo[3.3.1.1^3,7]dec-1-ylphenyl)-
• 2-Naphthalenecarboxylicacid,6-(4-Hydroxy-3-Tricyclo(3.3.1.1(3,7))Dec-1-Ylphen
• 6-(4-Hydroxy-3-Tricyclo(3.3.1.1(3,7))Dec-1-Ylphenyl)-2-Naphthalenecarboxylic
• 6-(4-Hydroxy-3-tricyclo[3.3.1.1^3,7]dec-1-ylphenyl)-2-naphthalenecarboxylic acid
• 6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthalenecarboxylic acid
• 6-[4-Hydroxy-3-(Tricyclo[3.3.1.1~3,7~]Dec-1-Yl)Phenyl]Naphthalene-2-Carboxylic Acid
• AHPN, 6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid
• C 5865
• Cd 437
• Cd 437/Ahpn
• 2-Naphthalenecarboxylic acid, 6-(4-hydroxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)-
• 6-(4-Hydroxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)-2-naphthalenecarboxylic acid

CD-437

CAS: 125316-60-1

Formula: C₂₇H₂₆O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 398.4935

Ref: IN-DA000NHE

O-Desmethyl Adapalene

CAS: 125316-60-1

Formula: C₂₇H₂₆O₃

Color and Shape: Off-White Solid

Molecular weight: 398.51

Ref: 4Z-A-100003

CD437

CAS: 125316-60-1

CD437

Purity: ≥98%

Molecular weight: 398.49g/mol

Ref: 54-BUP05861

O-Desmethyl Adapalene-13C6

CAS: 125316-60-1

Formula: C₂₁₁₃C₆H₂₆O₃

Color and Shape: White To Off-White Solid

Molecular weight: 404.46

Ref: 4Z-A-100011

6-[3-(1-Adamantyl)-4-Hydroxyphenyl]Naphthalene-2-Carboxylic Acid

CAS: 125316-60-1

6-[3-(1-Adamantyl)-4-Hydroxyphenyl]Naphthalene-2-Carboxylic Acid

Purity: 98%

Molecular weight: 398.49g/mol

Ref: 54-OR1023176

CD437

CAS: 125316-60-1

Formula: C₂₇H₂₆O₃

Molecular weight: 398.49

Ref: 7W-GK9655

CD 437

CAS: 125316-60-1

Formula: C₂₇H₂₆O₃

Purity: >93.0%(qNMR)

Color and Shape: White to Light gray to Light yellow powder to crystal

Molecular weight: 398.50

Ref: 3B-A3612

CD437

CAS: 125316-60-1

CD437 (AHPN) is a specifc Retinoic Acid Receptor γ (RARγ) agonist.

Formula: C₂₇H₂₆O₃

Purity: 98.92% - 99.63%

Color and Shape: Solid

Molecular weight: 398.49

Ref: TM-T4371

O-Desmethyl Adapalene

Controlled Product

CAS: 125316-60-1

Applications An intermediate in the preparation of Adapalene derivatives.
References Zinner, R., et al.: Mol. Cancer Ther., 8, 521 (2009), Virtanen, M., et al.: Exper. Dermatol., 19, 674 (2010),

Formula: C₂₇H₂₆O₃

Color and Shape: Neat

Molecular weight: 398.49

Ref: TR-D290680