CAS 1253282-31-3

Fmoc-L-Aph(L-Hor)-OH

Description:

Fmoc-L-Aph(L-Hor)-OH is a chemical compound that belongs to the class of amino acids and is commonly used in peptide synthesis. The "Fmoc" (9-fluorenylmethoxycarbonyl) group is a protective group that is often employed to protect the amino group during the synthesis of peptides, allowing for selective reactions at other functional groups. The "L-Aph" refers to L-α-aminophenylalanine, an amino acid derivative that incorporates a phenyl group, which can influence the compound's hydrophobicity and interactions in biological systems. The "(L-Hor)" indicates the presence of L-homophenylalanine, which is another amino acid variant that can provide unique properties to the peptide chain. The hydroxyl group (-OH) at the end of the molecule suggests that it can participate in further chemical reactions or serve as a site for conjugation. Overall, this compound is significant in the field of medicinal chemistry and biochemistry, particularly in the design and synthesis of bioactive peptides and pharmaceuticals.

Synonyms:

• Fmoc-Aph(Hor)-OH

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-((s)-2,6-dioxohexahydropyrimidine-4-carboxamido)phenyl)propanoic acid

CAS: 1253282-31-3

Formula: C₂₉H₂₆N₄O₇

Purity: 98%

Color and Shape: Solid

Molecular weight: 542.5393

Ref: IN-DA000NHX

Fmoc-Aph(Hor)-OH

CAS: 1253282-31-3

Fmoc-Aph(Hor)-OH

Purity: 98%

Molecular weight: 542.54g/mol

Ref: 54-OR1032132

Fmoc-Aph(Hor)-OH

CAS: 1253282-31-3

Formula: C₂₉H₂₆N₄O₇

Purity: 98%

Color and Shape: Solid

Molecular weight: 542.548

Ref: 10-F544948

Fmoc-Aph(Hor)-OH

CAS: 1253282-31-3

Fmoc-Aph(Hor)-OH is a high quality, versatile building block that can be used as a reagent and speciality chemical. It is a complex compound that has been shown to be useful in the synthesis of peptides, pharmaceuticals, and other organic and inorganic compounds. Fmoc-Aph(Hor)-OH has been used as a reaction component for the synthesis of various drugs including anti-inflammatory agents, antibiotics, and analgesics. Fmoc-Aph(Hor)-OH is an intermediate for the production of Boc-Lys(Fmoc)-OH which is used in the manufacture of anti-fungal agents such as Terbinafine hydrochloride.

Formula: C₂₉H₂₆N₄O₇

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 542.54 g/mol

Ref: 3D-FF153484

Fmoc-Aph(Hor)-OH (~10% THF) (Degarelix intermediate)

Controlled Product

CAS: 1253282-31-3

Applications Fmoc-Aph(Hor)-OH (CAS# 1253282-31-3) is an intermediate of degarelix, a pharmeceutical hormone used in the treatment of prostate cancer. Fmoc-Aph(Hor)-OH has been used as a building block in peptide elongation reactions.
References Guryanov, I.; et al.: WO 2017103275 (2017); Takahashi, D.; et al.: Angew. Chem. Int. Ed., 56, 7803 (2017).

Formula: C₂₉H₂₆N₄O₇

Color and Shape: Neat

Molecular weight: 542.54

Ref: TR-F647563