CAS 12542-36-8

gossypol-acetic acid

Description:

Gossypol-acetic acid is a derivative of gossypol, a natural polyphenolic compound found in cotton plants. It is characterized by its yellowish color and is known for its potential biological activities, including antitumor and antifertility effects. The compound has a complex structure featuring multiple hydroxyl groups, which contribute to its reactivity and interaction with biological systems. Gossypol-acetic acid exhibits solubility in organic solvents and limited solubility in water, which influences its application in various fields, including pharmaceuticals and agriculture. Its mechanism of action is thought to involve the inhibition of certain enzymes and interference with cellular processes. Due to its biological properties, gossypol-acetic acid has been studied for its potential use in cancer therapy and as a contraceptive agent. However, its toxicity and side effects necessitate careful consideration in therapeutic applications. Overall, gossypol-acetic acid represents a compound of interest in both medicinal chemistry and agricultural science, warranting further research to fully understand its capabilities and limitations.

Formula: C₃₂H₃₄O₁₀

InChI: InChI=1/C30H30O8.C2H4O2/c1-11(2)19-15-7-13(5)21(27(35)23(15)17(9-31)25(33)29(19)37)22-14(6)8-16-20(12(3)4)30(38)26(34)18(10-32)24(16)28(22)36;1-2(3)4/h7-12,33-38H,1-6H3;1H3,(H,3,4)

SMILES: CC(C)c1c2cc(C)c(c3c(C)cc4c(C(C)C)c(c(c(C=O)c4c3O)O)O)c(c2c(C=O)c(c1O)O)O.CC(=O)O

Synonyms:

• 1,1',6,6',7,7'-Hexahydroxy-3,3'-Dimethyl-5,5'-Di(Propan-2-Yl)-2,2'-Binaphthalene-8,8'-Dicarbaldehyde
• 1,1',6,6',7,7'-Hexahydroxy-3,3'-Dimethyl-5,5'-Di(Propan-2-Yl)-2,2'-Binaphthalene-8,8'-Dicarbaldehyde - Acetic Acid (1:1)
• Acetic acid gossypol
• At 101
• Ccris 3483
• Gossypol acetate
• Gossypol acetic acid
• aceticacidgossypol
• Gossypolaceticacidcomplex
• GOSSYPOLMONOACETICACID
• GOSSYPOLACETATE(GOSSYPOL-ACETICACID)
• 1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-5,5'-bis(1-methylethyl)[2,2'-binaphthalene]-8,8'-dicarboxaldehyde-acetic acid
• 1,1',6,6',7,7'-hexahydroxy-3,3'-dimethyl-5,5'-bis(1-methylethyl)[2,2'-binaphthalene]-8,8'-dicarboxaldehyde-acetic acid

Gossypol-acetic acid

CAS: 12542-36-8

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₃₂H₃₄O₁₀

Color and Shape: Yellow, Powder

Molecular weight: 578.61

Ref: 02-J63517

Gossypol-Acetic Acid

CAS: 12542-36-8

Gossypol-Acetic Acid

Purity: 98%

Molecular weight: 578.61g/mol

Ref: 54-OR1029026

Gossypol (acetic acid)

CAS: 12542-36-8

Gossypol (acetic acid)

Purity: ≥95%

Molecular weight: 578.61g/mol

Ref: 54-BUP13822

Gossypol-acetic acid

CAS: 12542-36-8

Formula: C₃₀H₃₀O₈·C₂H₄O₂

Purity: ≥ 97.0%

Color and Shape: Green to yellow-brown powder or crystals

Molecular weight: 578.61

Ref: 7W-GX3431

Acetate gossypol

CAS: 12542-36-8

Formula: C₃₂H₃₄O₁₀

Purity: 95%~99%

Molecular weight: 578.614

Ref: BP-BP0116

Gossypol Acetic Acid

CAS: 12542-36-8

Formula: C₃₀H₃₀O₈·C₂H₄O₂

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Green to Brown powder to crystal

Molecular weight: 578.61

Ref: 3B-G0543

Gossypol (acetic acid)

CAS: 12542-36-8

Gossypol acetic acid (AT101), a polyphenolic compound isolated from cottonseeds, binds with Bcl-2, Bcl-xL, Mcl-1, and does not inhibit BIR3 domain and BID.

Formula: C₃₂H₃₄O₁₀

Purity: 98.09%

Color and Shape: Yellow Crystal Powder

Molecular weight: 578.61

Ref: TM-T2730

Gossypol Acetate (Mixture)

CAS: 12542-36-8

Formula: C₃₂H₃₂O₉

Molecular weight: 560.60

Ref: 4Z-G-204001

Gossypol Acetate-d3 (mixture)

CAS: 12542-36-8

Formula: C₃₂H₂₉D₃O₉·C₃₂H₂₉D₃O₉

Molecular weight: 563.62 563.62

Ref: 4Z-G-204003

Gossypol Acetic Acid

Controlled Product

CAS: 12542-36-8

Applications Gossypol is a mixture of natural polyphenols isolated from the cotton plant. It causes spermatogenesis arrest in humans and also functions as an anti-malarial agent. Antiinflammatory. Anticancer.
References Huo, M. et al.: Int. Immunopharmacol., 15, 442 (2013); Coutinho, E. et al.: Contraception. 65, 259 (2002); Royer, R. et al.: J. Med. Chem., 29, 1799 (1986);

Formula: C₃₀H₃₀O₈·C₂H₄O₂

Color and Shape: Off White Solid

Molecular weight: 578.61

Ref: TR-G767900

Gossypol acetate

Controlled Product

CAS: 12542-36-8

Gossypol acetate is a polyphenolic aldehyde, which is a derivative of the natural compound gossypol found in cotton plants (Gossypium species). It is sourced predominantly from cottonseed oil, where gossypol acts as a natural defense mechanism against pests. The mode of action of gossypol acetate involves the inhibition of several dehydrogenase enzymes, which are crucial in energy metabolism. Additionally, it disrupts the function of Bcl-2 family proteins, leading to apoptotic cell death.

Formula: C₃₀H₃₀O₈•C₂H₄O₂

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 578.61 g/mol

Ref: 3D-FG32702

Gossypol Acetic Acid

CAS: 12542-36-8

Formula: C₃₂H₃₄O₁₀

Purity: 95%

Color and Shape: Solid

Molecular weight: 578.6063599999999

Ref: IN-DA00HI7F