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CAS 125441-01-2

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N-acetyl-(tyr(so3H)63)-hirudin *fragment 55-65

Description:
N-acetyl-(tyr(so3H)63)-hirudin *fragment 55-65 is a synthetic peptide derived from hirudin, a naturally occurring anticoagulant protein found in leeches. This specific fragment is characterized by its sequence of amino acids, which includes a sulfated tyrosine residue (tyr(so3H)63), contributing to its biological activity and interaction with various proteins. The N-acetylation at the N-terminus enhances its stability and solubility in biological systems. Hirudin and its derivatives are known for their potent inhibitory effects on thrombin, making them of significant interest in anticoagulant therapy. The CAS number 125441-01-2 uniquely identifies this compound in chemical databases, facilitating research and regulatory processes. Its structural features, including the presence of sulfated amino acids, influence its pharmacokinetics and pharmacodynamics, making it a valuable subject of study in medicinal chemistry and biochemistry. Overall, this compound exemplifies the complexity and specificity of peptide-based therapeutics in the context of coagulation and cardiovascular health.
Formula:C66H92N12O28S
Synonyms:
  • Acetyl-Hirudin (55-65) (sulfated)
  • Ac-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr(SO3H)-Leu-Gln-OH
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