The chemical substance referred to as "gly-arg-ala-asp-ser-pro-lys" is a peptide composed of a sequence of amino acids: glycine (Gly), arginine (Arg), alanine (Ala), aspartic acid (Asp), serine (Ser), proline (Pro), and lysine (Lys). This peptide is characterized by its specific sequence, which influences its biological activity and function. Peptides like this one can play crucial roles in various biological processes, including signaling, enzyme activity, and cellular communication. The presence of both polar and non-polar amino acids in the sequence contributes to its solubility and interaction with other biomolecules. The CAS number 125455-58-5 uniquely identifies this specific peptide in chemical databases, facilitating research and application in fields such as biochemistry, pharmacology, and biotechnology. Its properties, such as stability, reactivity, and potential therapeutic applications, can vary based on the sequence and the environment in which it is studied. Overall, this peptide exemplifies the complexity and significance of amino acid sequences in biological systems.

gly-arg-ala-asp-ser-pro-lys

125455-58-5: The chemical substance referred to as "gly-arg-ala-asp-ser-pro-lys" is a peptide composed of a sequence of amino acids: glycine (Gly), arginine (Arg), alanine (Ala), aspartic acid (Asp), serine (Ser), proline (Pro), and lysine (Lys). This peptide is characterized by its specific sequence, which influences its biological activity and function. Peptides like this one can play crucial roles in various biological processes, including signaling, enzyme activity, and cellular communication. The presence of both polar and non-polar amino acids in the sequence contributes to its solubility and interaction with other biomolecules. The CAS number 125455-58-5 uniquely identifies this specific peptide in chemical databases, facilitating research and application in fields such as biochemistry, pharmacology, and biotechnology. Its properties, such as stability, reactivity, and potential therapeutic applications, can vary based on the sequence and the environment in which it is studied. Overall, this peptide exemplifies the complexity and significance of amino acid sequences in biological systems.

Glycine-arginine-aspartate (GAA) is a mimic of the endothelium-derived vasoactive peptide, nitric oxide (NO). It has been shown to attenuate the inflammatory response by decreasing leukocyte adhesion and migration. GAA is also a potent inhibitor of vascular permeability and can attenuate edema in animal models. Studies have shown that GAA prevents microvascular damage following brain infarction. The mechanism of action for GAA is not fully understood, but it may be due to its ability to inhibit fibronectin breakdown, which leads to cerebral edema. GAA's activity on the endothelium may be due to its ability to mimic NO or inhibit sulfate synthesis.

CAS 125455-58-5

gly-arg-ala-asp-ser-pro-lys

H-Gly-Arg-Ala-Asp-Ser-Pro-Lys-OH acetate salt

Ref: 3D-FG109584