CAS 125464-42-8

Saclofen

Description:

Saclofen is a chemical compound classified as a selective antagonist of the GABA_B receptor, which plays a crucial role in the central nervous system. It is primarily used in research settings to investigate the physiological and pharmacological effects of GABA_B receptor modulation. Saclofen is known for its ability to inhibit the action of GABA, a major inhibitory neurotransmitter, thereby influencing various neurological processes. The compound is typically characterized by its solubility in water and organic solvents, making it suitable for various experimental applications. Its molecular structure includes a sulfonic acid group, contributing to its unique properties and interactions within biological systems. Saclofen has been studied for its potential therapeutic effects in conditions such as spasticity and pain management, although its clinical use is limited. Safety and handling precautions are essential when working with this compound, as with any chemical substance, to mitigate potential risks associated with its pharmacological activity.

Formula: C₉H₁₂ClNO₃S

InChI: InChI=1S/C9H12ClNO3S/c10-9-3-1-7(2-4-9)8(5-11)6-15(12,13)14/h1-4,8H,5-6,11H2,(H,12,13,14)

InChI key: InChIKey=JYLNVJYYQQXNEK-UHFFFAOYSA-N

SMILES: C(CS(=O)(=O)O)(CN)C1=CC=C(Cl)C=C1

Synonyms:

• (RS)-3-amino-2-(4-chlorophenyl)propylsulfonic acid
• 3-Amino-2-(4-chlorophenyl)propane-1-sulfonic acid
• Benzeneethanesulfonic acid, β-(aminomethyl)-4-chloro-
• β-(Aminomethyl)-4-chlorobenzeneethanesulfonic acid
• Saclofen

Benzeneethanesulfonic acid, β-(aminomethyl)-4-chloro-

CAS: 125464-42-8

Formula: C₉H₁₂ClNO₃S

Purity: 95%

Color and Shape: Solid

Molecular weight: 249.7145

Ref: IN-DA000NPW

Saclofen

CAS: 125464-42-8

Saclofen

Purity: ≥98%

Molecular weight: 249.71g/mol

Ref: 54-BUP05479

Saclofen

CAS: 125464-42-8

Formula: C₉H₁₂ClNO₃S

Molecular weight: 249.71

Ref: 7W-GK5385

Saclofen

CAS: 125464-42-8

Saclofen is a GABA analog and GABAB receptor antagonist, useful for studying inhibitory brain signals. IC50: 7.8 μM.

Formula: C₉H₁₂ClNO₃S

Purity: 99.17%

Color and Shape: White Crystalline Solid

Molecular weight: 249.71

Ref: TM-T4440

Saclofen

CAS: 125464-42-8

M02490 - Saclofen

Formula: C₉H₁₂ClNO₃S

Purity: >99%

Color and Shape: Solid

Molecular weight: 249.71

Ref: 10-M02490

Saclofen

Controlled Product

CAS: 125464-42-8

Applications Saclofen is a GABABR antagonist that has been shown to reduced leukocyte migration and increase Fos expression in T7-T11 sympathetic preganglionic neurons
References Yoon, S., et. al.: Neuropharmacology, 53, 677 (2007)

Formula: C₉H₁₂ClNO₃S

Color and Shape: Neat

Molecular weight: 249.714

Ref: TR-S080850