CAS 125464-52-0: Dehydronifedipine-D-6

Description:Dehydronifedipine-D-6 is a chemical compound that belongs to the class of dihydropyridine derivatives, which are primarily known for their role as calcium channel blockers. This specific compound is a deuterated form of nifedipine, a medication commonly used to treat hypertension and angina. The deuteration, indicated by the "D-6" in its name, refers to the substitution of hydrogen atoms with deuterium, a stable isotope of hydrogen, which can enhance the compound's stability and alter its pharmacokinetic properties. Dehydronifedipine-D-6 is characterized by its ability to selectively inhibit calcium influx through L-type calcium channels, leading to vasodilation and reduced cardiac workload. Its chemical structure features a dihydropyridine ring, which is essential for its biological activity. The compound is typically studied for its potential applications in pharmacology and medicinal chemistry, particularly in understanding the metabolism and efficacy of calcium channel blockers. As with any chemical substance, safety and handling precautions should be observed, especially in research settings.

Formula:C₁₇H₁₀D₆N₂O₆

InChI:InChI=1/C17H16N2O6/c1-9-13(16(20)24-3)15(14(10(2)18-9)17(21)25-4)11-7-5-6-8-12(11)19(22)23/h5-8H,1-4H3/i3D3,4D3

Synonyms:
Dimethyl 2,6-Dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylate-d6
2,6-Dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3,5-Di(methyl-d3) Ester
B 4759-d6

Found 3 products.

Product data	Purity	Price range	Estimated delivery
Nifedipine EP Impurity A-d6 (Dehydro Nifedipine-d6) REF: 4Z-N-071CAS: 125464-52-0	- - -	To inquire	Fri 03 Oct 25
Dehydro Nifedipine-d6 REF: TR-D229802CAS: 125464-52-0	- - -	315.00 €~2,078.00 €	Tue 14 Oct 25
3,5-Pyridinedicarboxylic acid, 2,6-dimethyl-4-(2-nitrophenyl)-, di(methyl-d3) ester (9CI) REF: IN-DA000NPVCAS: 125464-52-0	- - -	- - -	Discontinued product