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Sibutramine hydrochloride monohydrate

CAS 125494-59-9: Sibutramine hydrochloride monohydrate

Description:Sibutramine hydrochloride monohydrate is a synthetic compound primarily used as an appetite suppressant in the management of obesity. It functions as a serotonin-norepinephrine reuptake inhibitor, enhancing the levels of these neurotransmitters in the brain, which can lead to reduced hunger and increased satiety. The substance appears as a white to off-white crystalline powder and is soluble in water, making it suitable for various pharmaceutical formulations. Its chemical formula includes a hydrochloride salt and a monohydrate, indicating the presence of one water molecule per formula unit. Sibutramine has been associated with cardiovascular risks, leading to its withdrawal from many markets, including the European Union and the United States. As a controlled substance in several countries, it is important to handle it with caution and under appropriate regulations. Its pharmacokinetics involve extensive metabolism in the liver, and it is primarily excreted through urine. Overall, while it has been effective for weight management, its safety profile necessitates careful consideration in clinical use.

Formula:C17H26ClN·ClH·H2O

InChI:InChI=1S/C17H26ClN.ClH.H2O/c1-13(2)12-16(19(3)4)17(10-5-11-17)14-6-8-15(18)9-7-14;;/h6-9,13,16H,5,10-12H2,1-4H3;1H;1H2

InChI key:InChIKey=KFNNPQDSPLWLCX-UHFFFAOYSA-N

SMILES:Cl.ClC1=CC=C(C=C1)C2(CCC2)C(N(C)C)CC(C)C.O

  • Synonyms:
  • 1-(4-CHLOROPHENYL)-N,N-DIMETHYL-BETA-(2-METHYLPROPYL)CYCLOBUTANEMETHANAMINE HYDROCHLORIDE hydrate
  • 1-[1-(4-chlorophenyl)cyclobutyl]-N,N,3-trimethylbutan-1-amine hydrochloride hydrate
  • Cyclobutanemethanamine, 1-(4-chlorophenyl)-N,N-dimethyl-α-(2-methylpropyl)-, hydrochloride, hydrate (1:1:1)
  • Cyclobutanemethanamine, 1-(4-chlorophenyl)-N,N-dimethyl-α-(2-methylpropyl)-, hydrochloride, monohydrate
  • Intermediate of Sibutramine hydrochloride hydrate
  • SIBUTRAMINEHYDROCHLORIDE hydrate
  • Sibutramine Hcl Monohydrate
  • Sibutramine Hcl hydrate
  • Sibutramine Hydrochloride Monohydrate
  • Sibutramine・HCL hydrate
  • See more synonyms
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Cyclobutanemethanamine, 1-(4-chlorophenyl)-N,N-dimethyl-α-(2-methylpropyl)-, hydrochloride, hydrate (1:1:1)

CAS:125494-59-9

Ref: IN-DA000NQA

Undefined sizeTo inquire
Estimated delivery in United States, on Monday 3 Mar 2025
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Sibutramine hydrochloride

CAS:125494-59-9

Ref: 7W-GP4519

1g61.00 €
5g147.00 €
Estimated delivery in United States, on Tuesday 4 Mar 2025
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Ref: 3U-D7102

10mg388.00 €
50mg1,260.00 €
Estimated delivery in United States, on Wednesday 5 Mar 2025
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Sibutramine Hydrochloride Monohydrate

Controlled Product
CAS:125494-59-9

Ref: 86-MM0991.00

100mg1,444.00 €
Estimated delivery in United States, on Thursday 6 Mar 2025
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Sibutramine, Hydrochloride Monohydrate

Controlled Product
CAS:125494-59-9

Ref: TR-S422500

25mg260.00 €
50mg326.00 €
500mg2,242.00 €
Estimated delivery in United States, on Thursday 13 Mar 2025
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Sibutramine hydrochloride monohydrate

Controlled Product
CAS:125494-59-9

Ref: 3D-FS27826

1g1,252.00 €
2g2,003.00 €
100mg334.00 €
250mg629.00 €
500mg998.00 €
Estimated delivery in United States, on Friday 14 Mar 2025
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Sibutramine HCl monohydrate - Bio-X ™

Controlled Product
CAS:125494-59-9

Ref: 3D-BS164401

10mg149.00 €
Estimated delivery in United States, on Friday 14 Mar 2025
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