CAS 125533-88-2

Mofarotene

Description:

Mofarotene, with the CAS number 125533-88-2, is a synthetic retinoid, a class of compounds related to vitamin A, known for their ability to modulate cellular growth and differentiation. It exhibits properties that make it of interest in the treatment of various dermatological conditions and certain types of cancer. Mofarotene functions primarily through the activation of retinoic acid receptors (RARs), influencing gene expression and cellular processes. Its chemical structure includes a series of conjugated double bonds, which contribute to its biological activity and stability. Mofarotene is typically administered topically or systemically, depending on the condition being treated. The compound has been studied for its potential in managing skin disorders such as psoriasis and for its anti-tumor effects. However, like other retinoids, it may have side effects, including skin irritation and teratogenicity, necessitating careful consideration in its use, particularly in pregnant individuals. Overall, Mofarotene represents a significant area of research in pharmacology and dermatology.

Formula: C₂₉H₃₉NO₂

InChI: InChI=1S/C29H39NO2/c1-22(24-8-11-26-27(21-24)29(4,5)13-12-28(26,2)3)20-23-6-9-25(10-7-23)32-19-16-30-14-17-31-18-15-30/h6-11,20-21H,12-19H2,1-5H3/b22-20+

InChI key: InChIKey=OUQPTBCOEKUHBH-LSDHQDQOSA-N

SMILES: CC1(C)C=2C(C(C)(C)CC1)=CC=C(\C(=C\C3=CC=C(OCCN4CCOCC4)C=C3)\C)C2

Synonyms:

• Morpholine, 4-[2-[4-[(1E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl]phenoxy]ethyl]-
• 4-[2-[4-[(1E)-2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propen-1-yl]phenoxy]ethyl]morpholine
• Morpholine, 4-[2-[4-[2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl]phenoxy]ethyl]-, (E)-
• Morpholine, 4-[2-[4-[(1E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propen-1-yl]phenoxy]ethyl]-
• Ro 40-8757

Mofarotene

CAS: 125533-88-2

Mofarotene

Purity: ≥98%

Molecular weight: 433.63g/mol

Ref: 54-BUP03961

Mofarotene

CAS: 125533-88-2

Mofarotene (Ro-40-8757) is a small molecule compound that shows considerable antitumor activity in many cancer cell lines and can be used for the treatment of

Formula: C₂₉H₃₉NO₂

Purity: 99.96%

Color and Shape: Solid

Molecular weight: 433.63

Ref: TM-T68104