CAS 125533-88-2: Mofarotene

Description: Mofarotene, with the CAS number 125533-88-2, is a synthetic retinoid, a class of compounds related to vitamin A, known for their ability to modulate cellular growth and differentiation. It exhibits properties that make it of interest in the treatment of various dermatological conditions and certain types of cancer. Mofarotene functions primarily through the activation of retinoic acid receptors (RARs), influencing gene expression and cellular processes. Its chemical structure includes a series of conjugated double bonds, which contribute to its biological activity and stability. Mofarotene is typically administered topically or systemically, depending on the condition being treated. The compound has been studied for its potential in managing skin disorders such as psoriasis and for its anti-tumor effects. However, like other retinoids, it may have side effects, including skin irritation and teratogenicity, necessitating careful consideration in its use, particularly in pregnant individuals. Overall, Mofarotene represents a significant area of research in pharmacology and dermatology.

Formula: C₂₉H₃₉NO₂

InChI: InChI=1S/C29H39NO2/c1-22(24-8-11-26-27(21-24)29(4,5)13-12-28(26,2)3)20-23-6-9-25(10-7-23)32-19-16-30-14-17-31-18-15-30/h6-11,20-21H,12-19H2,1-5H3/b22-20+

InChI key: InChIKey=OUQPTBCOEKUHBH-LSDHQDQOSA-N

SMILES: O(C1=CC=C(C=C1)C=C(C2=CC=C3C(=C2)C(C)(C)CCC3(C)C)C)CCN4CCOCC4

Synonyms:

• Morpholine, 4-[2-[4-[(1E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl]phenoxy]ethyl]-
• 4-[2-[4-[(1E)-2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propen-1-yl]phenoxy]ethyl]morpholine
• Morpholine, 4-[2-[4-[2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl]phenoxy]ethyl]-, (E)-
• Morpholine, 4-[2-[4-[(1E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propen-1-yl]phenoxy]ethyl]-
• Ro 40-8757

Mofarotene

CAS: 125533-88-2

• Purity: 99.36%
• Molecular weight: 433.63g/mol

Mofarotene

CAS: 125533-88-2

Mofarotene (Ro-40-8757) is a small molecule compound that shows considerable antitumor activity in many cancer …

• Formula: C₂₉H₃₉NO₂
• Purity: 99.36%
• Color and Shape: Liquid
• Molecular weight: 433.63