CAS 1255517-76-0
:PF-4708671
Description:
PF-4708671, with the CAS number 1255517-76-0, is a small molecule that serves as a selective inhibitor of the protein kinase mTOR (mechanistic target of rapamycin). This compound is primarily investigated for its potential therapeutic applications in cancer treatment and other diseases characterized by dysregulated mTOR signaling. PF-4708671 exhibits a high degree of specificity for mTOR, which is a central regulator of cell growth, proliferation, and survival. The inhibition of mTOR by PF-4708671 can lead to reduced protein synthesis and cell cycle arrest, making it a candidate for combination therapies in oncology. Additionally, the compound has been studied for its effects on metabolic processes and its potential role in addressing conditions such as obesity and diabetes. As with many investigational drugs, the pharmacokinetics, bioavailability, and safety profile of PF-4708671 are subjects of ongoing research to better understand its efficacy and potential side effects in clinical settings.
Formula:C19H21F3N6
Synonyms:- 1H-Benzimidazole, 2-[[4-(5-ethyl-4-pyrimidinyl)-1-piperazinyl]methyl]-6-(trifluoromethyl)-
- 2-[[4-(5-Ethyl-4-pyrimidinyl)-1-piperazinyl]methyl]-6-(trifluoromethyl)-1H-benzimidazole PF-4708671
- CS-869
- PF-4708671 USP/EP/BP
- PF 4708671
- PF 4708671 - PF 04708671
- 2-[[4-(5-Ethylpyrimidin-4-yl)piperazin-1-yl]methyl]-5-(trifluoromethyl)-1H-benzo[d]imidazole
- PF4708671/PF-4708671
- PF-04708671
- 2-[[4-(5-ethyl-4-pyriMidinyl)-1-piperazinyl]Methyl]-6-(trifluoroMethyl)-1H-benziMidazole
- 2-[[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl]-6-(trifluoromethyl)-1H-benzimidazole
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Found 6 products.
2-[[4-(5-Ethylpyrimidin-4-yl)piperazin-1-yl]methyl]-5-(trifluoromethyl)-1H-benzo[d]imidazole
CAS:Formula:C19H21F3N6Purity:98%Color and Shape:SolidMolecular weight:390.4054PF-4708671
CAS:PF-4708671Formula:C19H21F3N6Purity:≥98%Color and Shape: white solidMolecular weight:390.40544g/molPF-4708671
CAS:PF-4708671 is a cell-permeable inhibitor of p70 ribosomal S6 kinase (S6K1 isoform) .In cell-free assays, PF-4708671 is potent for S6K1(Ki50=20 nM, IC50=160 nM).Formula:C19H21F3N6Purity:99.48% - 99.98%Color and Shape:SolidMolecular weight:390.41PF 4708671
CAS:Inhibitor of p70 ribosomal kinase S5K1Formula:C19H21F3N6Purity:Min. 95%Color and Shape:PowderMolecular weight:390.41 g/mol
![2-[[4-(5-Ethylpyrimidin-4-yl)piperazin-1-yl]methyl]-5-(trifluoromethyl)-1H-benzo[d]imidazole](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA009CE5.jpg&w=3840&q=75)
