CAS 125602-71-3

Bepotastine

Description:

Bepotastine is an antihistamine medication primarily used for the treatment of allergic conjunctivitis and other allergic conditions. It functions as a selective H1 receptor antagonist, effectively blocking the action of histamine, a compound involved in allergic responses. Bepotastine is known for its rapid onset of action and relatively low sedative effects compared to first-generation antihistamines, making it suitable for use in patients who need to avoid drowsiness. The substance is typically administered as an ophthalmic solution, allowing for direct application to the affected area. Its chemical structure includes a piperidine ring, contributing to its pharmacological properties. Bepotastine is generally well-tolerated, with a low incidence of side effects, although some patients may experience mild local irritation or discomfort upon application. As with any medication, it is essential for users to follow prescribed dosages and consult healthcare professionals regarding potential interactions with other medications or underlying health conditions.

Formula: C₂₁H₂₅ClN₂O₃

InChI: InChI=1S/C21H25ClN2O3/c22-17-8-6-16(7-9-17)21(19-4-1-2-12-23-19)27-18-10-14-24(15-11-18)13-3-5-20(25)26/h1-2,4,6-9,12,18,21H,3,5,10-11,13-15H2,(H,25,26)/t21-/m0/s1

InChI key: InChIKey=YWGDOWXRIALTES-NRFANRHFSA-N

SMILES: [C@H](OC1CCN(CCCC(O)=O)CC1)(C2=CC=C(Cl)C=C2)C3=CC=CC=N3

Synonyms:

• (S)-4-[4-(4-chlorophenyl-2-pyridylmethoxy)piperidinyl]butyric acid
• (S)-Bepotastine
• 1-Piperidinebutanoic acid, 4-[(S)-(4-chlorophenyl)-2-pyridinylmethoxy]-
• 4-((4-Chlorophenyl)-2-pyridinylmethoxy)-1-piperidinebutanoic acid
• 4-(4-[(1S)(4-Chlorophenyl)-2-Pyridylmethoxy]Piperidyl)Butanoic Acid
• 4-[(S)-(4-Chlorophenyl)-2-pyridinylmethoxy]-1-piperidinebutanoic acid
• 4-{4-[(4-Chlorophenyl)(Pyridin-2-Yl)Methoxy]Piperidin-1-Yl}Butanoic Acid
• 4-{4-[(S)-(4-chlorophenyl)(pyridin-2-yl)methoxy]piperidin-1-yl}butanoic acid
• Betotastine
• Betotastine Besilate
• Bepotastine

1-Piperidinebutanoic acid, 4-[(S)-(4-chlorophenyl)-2-pyridinylmethoxy]-

CAS: 125602-71-3

Formula: C₂₁H₂₅ClN₂O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 388.8878

Ref: IN-DA000NY5

Bepotastine

CAS: 125602-71-3

Bepotastine

Purity: ≥98%

Molecular weight: 388.89g/mol

Ref: 54-BUP12959

Bepotastine

CAS: 125602-71-3

Bepotastine (Bepotastine free base) free base is a histamine 1 (H1) receptor antagonis.

Formula: C₂₁H₂₅ClN₂O₃

Purity: 99.75%

Color and Shape: Solid

Molecular weight: 388.89

Ref: TM-T7893

Bepotastine >90%

Controlled Product

CAS: 125602-71-3

Applications Bepotastine is a histamine H1 receptor antagonist. Bepotastine suppresses some allergic inflammatory processes such as allergic rhinitis, chronic urticaria or pruritus associated with skin conditions (eczema/dermatitis, prurigo or pruritus cutaneus).
References Kaminuma, O. et al.: Biol. Pharm. Bull., 21, 411 (1998); Kitaba, S. et al.: J. Allergy, No pp. given (2008); Lyseng-Williamson, K.A., Drugs, 70, 1579 (2010);

Formula: C₂₁H₂₅ClN₂O₃

Purity: >90%

Color and Shape: Neat

Molecular weight: 388.89

Ref: TR-B316095

Bepotastine besilate

CAS: 125602-71-3

H1-receptor antagonist

Formula: C₂₁H₂₅ClN₂O₃•C₆H₆O₃S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 547.06 g/mol

Ref: 3D-FB61374

(+)-(S)-4-[4-[1-(4-CHLOROPHENYL)-1-(2-PYRIDYL)METHOXY]PIPERIDIN-1-YL]BUTYRIC ACID

CAS: 125602-71-3

Purity: 98%

Molecular weight: 388.8900146

Ref: 10-F808643