CAS 125622-13-1

dactylocycline B

Description:

Dactylocycline B is a naturally occurring antibiotic belonging to the class of compounds known as tetracyclines. It is derived from the fermentation of certain species of Streptomyces bacteria. This compound exhibits a broad spectrum of antibacterial activity, particularly against Gram-positive and some Gram-negative bacteria, making it valuable in the field of microbiology and medicine. Dactylocycline B functions by inhibiting bacterial protein synthesis, specifically by binding to the 30S ribosomal subunit, which prevents the incorporation of amino acids into peptides. This mechanism of action is characteristic of tetracyclines. In addition to its antibacterial properties, dactylocycline B may also possess anti-inflammatory and antitumor activities, although further research is needed to fully understand these potential effects. The compound's stability, solubility, and pharmacokinetic properties are important factors that influence its therapeutic applications. As with other tetracyclines, it is essential to consider potential side effects and resistance patterns when using dactylocycline B in clinical settings.

Formula: C₃₁H₃₈ClN₃O₁₄

InChI: InChI=1/C31H38ClN3O14/c1-11-26(47-7)28(2,35(44)45)10-15(48-11)49-29(3)12-9-30(42)23(34(4)5)22(38)18(27(33)41)25(40)31(30,43)24(39)16(12)21(37)17-13(36)8-14(46-6)20(32)19(17)29/h8,11-12,15,23,26,36-37,41-43H,9-10,33H2,1-7H3/b27-18-

Synonyms:

• (9Z)-9-[amino(hydroxy)methylidene]-4-chloro-7-(dimethylamino)-1,6a,10a,12-tetrahydroxy-3-methoxy-5-methyl-8,10,11-trioxo-5,5a,6,6a,7,8,9,10,10a,11-decahydrotetracen-5-yl 2,3,6-trideoxy-3-methyl-4-O-methyl-3-nitrohexopyranoside
• 2-Naphthacenecarboxamide, 7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,4a,10,12,12a-pentahydroxy-8-methoxy-6-methyl-1,11-dioxo-6-((2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitro-alpha-L-arabino-hexopyranosyl)oxy)-, (4R-(4alpha,4aalpha,5aalpha,6alpha,12aalpha))-
• Dactylocycline B

Dactylocycline B

CAS: 125622-13-1

Dactylocyclines B: novel tetracycline from Dactylosporangium, fights tetracycline-resistant microbes.

Formula: C₃₁H₃₈ClN₃O₁₄

Color and Shape: Solid

Molecular weight: 712.1

Ref: TM-T23957