CAS 1256345-60-4

2-Fluoro-6-hydroxyphenylboronic acid

Description:

2-Fluoro-6-hydroxyphenylboronic acid is an organoboron compound characterized by the presence of a boronic acid functional group attached to a phenyl ring that also contains a hydroxyl group and a fluorine substituent. This compound typically exhibits a white to off-white solid appearance and is soluble in polar solvents such as water and alcohols, owing to the presence of the hydroxyl and boronic acid groups. The boronic acid moiety allows for the formation of reversible covalent bonds with diols, making it useful in various applications, including organic synthesis and medicinal chemistry. The fluorine atom can influence the compound's electronic properties and reactivity, potentially enhancing its biological activity or selectivity in chemical reactions. Additionally, the compound may exhibit interesting properties such as pH sensitivity due to the acidic nature of the boronic acid group, which can affect its behavior in different environments. Overall, 2-Fluoro-6-hydroxyphenylboronic acid is a versatile compound with potential applications in drug development and materials science.

Boronic acid, B-(2-fluoro-6-hydroxyphenyl)-

CAS: 1256345-60-4

Formula: C₆H₆BFO₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 155.9194

Ref: IN-DA000O05

2-Fluoro-6-hydroxyphenylboronic acid

CAS: 1256345-60-4

2-Fluoro-6-hydroxyphenylboronic acid

Formula: C₆H₆BFO₃

Purity: 92%

Color and Shape: white to grey solid

Molecular weight: 155.92g/mol

Ref: 54-PC412426

2-Fluoro-6-hydroxyphenylboronic Acid

Controlled Product

CAS: 1256345-60-4

Stability Form Trimer in solution
Applications 2-Fluoro-6-hydroxyphenylboronic Acid is a synthetic reagent used in the preparation of alkylene-bridged [(3,4-dihydro-2H-benzo[b][1,4]oxazinyl) or (piperidinyl)(biphenyl-3-yl)pyrazolo[1,5-a]pyrimidinyl](tert-butoxy)acetic acid derivatives as HIV integrase inhibitors for treating HIV infection.
References Naidu, N., et al.: PCT Int. Appl. (2014), WO 2014028384 A1 20140220;

Formula: C₆H₆BFO₃

Color and Shape: White To Off-White

Molecular weight: 155.92

Ref: TR-F489660

(2-Fluoro-6-hydroxyphenyl)boronic acid

CAS: 1256345-60-4

Formula: C₆H₆BFO₃

Purity: 95%

Color and Shape: Solid, Crystalline Powder or Powder

Molecular weight: 155.92

Ref: 10-F447574