
CAS 1256584-80-1
:9-ethyl-8-iodo-6,6-diMethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
Description:
9-Ethyl-8-iodo-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile is a complex organic compound characterized by its unique structural features, including a benzo[b]carbazole core, which is a fused polycyclic aromatic system. The presence of an ethyl group and an iodine atom at specific positions contributes to its chemical reactivity and potential biological activity. The compound also contains a carbonitrile functional group, which can influence its solubility and polarity. The dimethyl groups enhance steric hindrance, potentially affecting the compound's interactions with biological targets. Additionally, the keto group (11-oxo) may play a role in its reactivity and stability. This compound may exhibit interesting pharmacological properties, making it a subject of interest in medicinal chemistry. However, detailed studies would be necessary to fully understand its properties, including solubility, melting point, and potential applications in drug development or other fields. Safety and handling precautions should be observed due to the presence of iodine and the complexity of the compound.
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 6 products.
5H-Benzo[b]carbazole-3-carbonitrile, 9-ethyl-6,11-dihydro-8-iodo-6,6-dimethyl-11-oxo-
CAS:Formula:C21H17IN2OPurity:98%Color and Shape:SolidMolecular weight:440.27699-Ethyl-8-iodo-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
CAS:9-Ethyl-8-iodo-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrilePurity:99%Molecular weight:440.28g/mol9-Ethyl-8-iodo-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
CAS:Purity:98%Molecular weight:440.283996582031259-Ethyl-8-iodo-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
CAS:Controlled Product<p>Stability Light Sensitive<br>Applications 9-Ethyl-8-iodo-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile is an intermediate of Alectinib (C183360), a highly selective and potent anaplastic lymphoma kinase (ALK) inhibitor capable of blocking the resistant gatekeeper mutant, which results in reduced cell growth. Process impurity.<br>References Kinoshita, K. et al.: J. Med. Chem., 64, 6286 (2011); Sakamoto, H., et al.: Cancer Cell., 19, 679 (2011); Kinoshita, K., et al.: Bio-org. Medn., 20, 1271 (2012);<br></p>Formula:C21H17IN2OColor and Shape:NeatMolecular weight:440.289-Ethyl-8-iodo-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
CAS:<p>Alectinib intermediate</p>Formula:C21H17IN2OPurity:Min. 95%Color and Shape:White PowderMolecular weight:440.28 g/mol





