CAS 125678-68-4

Myristoyl-Lys-Arg-Thr-Leu-Arg-OH

Description:

Myristoyl-Lys-Arg-Thr-Leu-Arg-OH, with the CAS number 125678-68-4, is a synthetic peptide that features a myristoyl group, which is a fatty acid chain that enhances membrane permeability and cellular uptake. This peptide consists of a sequence of amino acids, including lysine (Lys), arginine (Arg), threonine (Thr), leucine (Leu), and another arginine, indicating its potential role in biological processes such as cell signaling or membrane interaction. The presence of basic amino acids like lysine and arginine suggests that the peptide may have a positive charge at physiological pH, which can influence its interaction with negatively charged cellular components. Additionally, the myristoyl modification can facilitate the peptide's insertion into lipid membranes, making it useful in drug delivery systems or as a tool in molecular biology. Overall, this compound's characteristics make it a subject of interest in research related to peptide chemistry, pharmacology, and biochemistry.

Formula: C₄₂H₈₂N₁₂O₈

InChI: InChI=1/C42H82N12O8/c1-5-6-7-8-9-10-11-12-13-14-15-23-34(56)50-30(20-16-17-24-43)36(57)51-31(21-18-25-48-41(44)45)37(58)54-35(29(4)55)39(60)53-33(27-28(2)3)38(59)52-32(40(61)62)22-19-26-49-42(46)47/h28-33,35,55H,5-27,43H2,1-4H3,(H,50,56)(H,51,57)(H,52,59)(H,53,60)(H,54,58)(H,61,62)(H4,44,45,48)(H4,46,47,49)/t29-,30+,31+,32+,33+,35+/m1/s1

Synonyms:

• N-Myristoyl-lysyl-arginyl-threonyl-leucyl-arginine
• Mlatla
• N-Myristyl-lys-arg-thr-leu-arg
• N2-(N-(N-(N2-(N2-(1-Oxotetradecyl)-L-lysyl)-L-arginyl)-L-threonyl)-L-leucyl)-L-arginine
• L-Arginine, N2-(N-(N-(N2-(N2-(1-oxotetradecyl)-L-lysyl)-L-arginyl)-L-threonyl)-L-leucyl)-
• N~2~-tetradecanoyl-L-lysyl-N~5~-(diaminomethylidene)-L-ornithyl-L-threonyl-L-leucyl-N~5~-(diaminomethylidene)-L-ornithine

L-Arginine, N2-(1-oxotetradecyl)-L-lysyl-L-arginyl-L-threonyl-L-leucyl-

CAS: 125678-68-4

Formula: C₄₂H₈₂N₁₂O₈

Molecular weight: 883.1761

Ref: IN-DA000OBT

N-Myristoyl-Lys-Arg-Thr-Leu-Arg

CAS: 125678-68-4

N-Myristoyl-Lys-Arg-Thr-Leu-Arg: PKC inhibitor, IC50=75μM, blocks IL-2 in Jurkat cells.

Formula: C₄₂H₈₂N₁₂O₈

Color and Shape: Solid

Molecular weight: 883.18

Ref: TM-T76185

Myristoyl-Lys-Arg-Thr-Leu-Arg-OH

CAS: 125678-68-4

Myristoyl-Lys-Arg-Thr-Leu-Arg-OH is a synthetic compound that interacts with tyrosine kinase substrate proteins. It inhibits the activation of these proteins and prevents the phosphorylation of tyrosine residues in other substrate proteins. Myristoyl-Lys-Arg-Thr-Leu-Arg-OH has been shown to have potent inhibitory activity against IL2 receptor and adriamycin, which are protein kinases that play important roles in the death pathway.

Formula: C₄₂H₈₂N₁₂O₈

Purity: Min. 95%

Molecular weight: 883.18 g/mol

Ref: 3D-FM111032