CAS 1256963-02-6

4-(3-chloro-5-propan-2-yl-1H-pyrazol-4-yl)-N-[5-[4-(dimethylamino)piperidin-1-yl]pyridin-2-yl]pyrimidin-2-amine

Description:

The chemical substance known as "4-(3-chloro-5-propan-2-yl-1H-pyrazol-4-yl)-N-[5-[4-(dimethylamino)piperidin-1-yl]pyridin-2-yl]pyrimidin-2-amine" with CAS number 1256963-02-6 is a complex organic compound characterized by its multi-cyclic structure, which includes a pyrazole, pyridine, and pyrimidine moiety. This compound features a chloro substituent and an isopropyl group, contributing to its unique chemical properties and potential biological activity. The presence of a dimethylamino group suggests that it may exhibit basic properties, which can influence its solubility and interaction with biological targets. Such compounds are often investigated for their pharmacological potential, particularly in the context of drug development, where they may act as inhibitors or modulators of specific biological pathways. The intricate arrangement of functional groups and rings in this molecule may also affect its reactivity, stability, and overall efficacy in therapeutic applications. Further studies would be necessary to elucidate its specific properties and potential uses in medicinal chemistry.

Synonyms:

• Cdk4-In-1
• 4-(5-Chloro-3-isopropyl-1H-pyrazol-4-yl)-N-(5-(4-(dimethylamino)piperidin-1-yl)pyridin-2-yl)pyrimidin-2-amine

4-(5-Chloro-3-isopropyl-1H-pyrazol-4-yl)-N-(5-(4-(dimethylamino)piperidin-1-yl)pyridin-2-yl)pyrimidin-2-amine

CAS: 1256963-02-6

Formula: C₂₂H₂₉ClN₈

Purity: 98%

Color and Shape: Solid

Molecular weight: 440.9723

Ref: IN-DA009FVG

CDK 4/6 Inhibitor-D6

Controlled Product

CAS: 1256963-02-6

Formula: C₂₂D₆H₂₃ClN₈

Color and Shape: Neat

Molecular weight: 447.009

Ref: TR-C228132

CDK 4/6 Inhibitor

Controlled Product

CAS: 1256963-02-6

Formula: C₂₂H₂₉ClN₈

Color and Shape: Neat

Molecular weight: 440.972

Ref: TR-C228130

CDK 4/6 Inhibitor-D6

CAS: 1256963-02-6

CDK 4/6 Inhibitor-D6 is a monoclonal antibody that inhibits the activity of CDK4 and CDK6, which are key enzymes in the cell cycle that regulate the progression from G1 to S phase. This drug has been shown to inhibit tumor growth in xenograft tumor models. It has also been shown to induce apoptosis in cancer cells by inhibiting the methyltransferase activity of EZH2. The pharmacokinetic properties of this drug have been characterized in a multivariate logistic regression model, and it may serve as a potential biomarker for prostate cancer treatment.

Formula: C₂₂H₂₃D₆ClN₈

Purity: Min. 95%

Molecular weight: 447.01 g/mol

Ref: 3D-GAC96302

CDK4-IN-1

CAS: 1256963-02-6

CDK4 inhibitor is a novel and specific CDK4/Cyclin D1 inhibitor with an IC50 of 10 nM; 1500 and 500 fold than CDK1/Cyclin B (IC50>15 uM) and CDK2/Cyclin A (IC50

Formula: C₂₂H₂₉ClN₈

Purity: 98%

Color and Shape: Solid

Molecular weight: 440.97

Ref: TM-T2082