CAS 1257-08-5

(-)-epicatechin gallate

Description:

(-)-Epicatechin gallate is a flavonoid compound belonging to the class of catechins, which are polyphenolic compounds found in various plants, particularly in tea leaves. It is characterized by its antioxidant properties, which are attributed to its ability to scavenge free radicals and chelate metal ions, thereby contributing to its potential health benefits. The compound is a gallate ester of (-)-epicatechin, featuring a galloyl group that enhances its biological activity. (-)-Epicatechin gallate is known for its role in promoting cardiovascular health, improving metabolic functions, and exhibiting anti-inflammatory effects. Additionally, it has been studied for its potential anticancer properties, as it may inhibit tumor growth and induce apoptosis in cancer cells. The compound is soluble in water and organic solvents, making it versatile for various applications in food, pharmaceuticals, and cosmetics. Its presence in green tea and other plant-based sources highlights its significance in nutrition and health research. Overall, (-)-epicatechin gallate is a compound of considerable interest due to its diverse biological activities and potential therapeutic applications.

Formula: C₂₂H₁₈O₁₀

InChI: InChI=1/C22H18O10/c23-11-6-18-12(8-17(28)21(31-18)9-1-2-13(24)14(25)3-9)19(7-11)32-22(30)10-4-15(26)20(29)16(27)5-10/h1-7,17,21,23-29H,8H2/t17-,21+/m0/s1

InChI key: InChIKey=LSHVYAFMTMFKBA-TZIWHRDSSA-N

SMILES: O(C(=O)C1=CC(O)=C(O)C(O)=C1)[C@H]2[C@H](OC=3C(C2)=C(O)C=C(O)C3)C4=CC(O)=C(O)C=C4

Synonyms:

• (-)-Epicatechin 3-O-gallate
• (-)-Epicatechin 3-gallate
• (-)-Epicatechol gallate
• (-)-epi-Catechin 3-O-gallate
• (2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate
• (2R,3S)-2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-3,4-dihydro-2H-chromen-5-yl 3,4,5-trihydroxybenzoate
• 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate
• 3-Galloyl-(-)-epicatechin
• 3-Galloyl-(2R,3R)-(-)-Epicatechin
• 3-O-Galloyl-(-)-epicatechin
• 3-O-Galloylepicatechin
• <span class="text-smallcaps">L</span>-Epicatechin gallate
• Benzoic acid, 3,4,5-trihydroxy-, (2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran-3-yl ester
• Benzoic acid, 3,4,5-trihydroxy-, 2-(3,4-dihydroxyphenyl)-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran-3-yl ester, (2R-cis)-
• ECG
• Epicatechol 3-gallate
• Gallic acid, 3-ester with epicatechol, (-)-
• L-Ecg
• (-)-CIS-2-(3,4-DIHYDROXYPHENYL)-3,4-DIHYDRO-1(2H)-BENZOPYRAN-3,5,7-TRIOL 3-GALLATE
• (2r-cis)-oxy-2h-1-benzopyran-3-yleste
• benzoicacid,3,4,5-trihydroxy-,2-(3,4-dihydroxyphenyl)-3,4-dihydro-5,7-dihydr
• (-)-ECG:BENZOICACID, 3,4,5-TRIHYDROXY-, 2-(3,4-DIHYDROXYPHENYL)-3,4-DIHYDRO-5,7-DIHYDROXY-2H-1-BENZOPYRAN-3-YLESTER, (2R-CIS)-,
• (2R,3R)-2-(3,4-DIHYDROXYPHENYL)-3,4-DIHYDRO-1(2H)-BENZOPYRAN-3,5,7-TRIOL 3-(3,4,5-TRIHYDROXYBENZOATE)
• (-)-EPICATECHIN GALLATE
• EPICATECHIN GALLATE(ECG) FROM GREEN TEA 50% BY HPLC
• (-)-CIS-3,3',4',5,7-PENTAHYDROXYFLAVANE 3-GALLATE
• EPICATECHIN GALLATE
• 3-gallate,(-)-epicatecho
• EPICATECHIN GALLATE(ECG) FROM GREEN TEA 70% BY HPLC
• (-)-epicatecholgallate
• EPICATECHIN GALLATE, (-)-SNAP-N-SHOOT 0.1mg/ml(P)
• EPICATECHIN GALLATE, (-)-
• EPICATECHIN GALLATE, (-)-(P)

(-)-Epigallocatechin Gallate Hydrate

CAS: 1257-08-5, 989-51-5

Formula: C₂₂H₁₈O₁₁·xH₂O

Purity: >98.0%(HPLC)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 458.38 (as Anhydrous)

Ref: 3B-E0694

(-)-Epicatechin gallate

CAS: 1257-08-5

A natural product from green tea that induces apoptosis

Formula: C₂₂H₁₈O₁₀

Color and Shape: White to off-white, Powder

Molecular weight: 442.38

Ref: 02-J60814

(-)-Epicatechin gallate

CAS: 1257-08-5

(-)-Epicatechin gallate analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₂₂H₁₈O₁₀

Purity: (HPLC) ≥98%

Color and Shape: Powder

Molecular weight: 442.37

Ref: 11-0978S

(-)-Epicatechingallate

CAS: 1257-08-5

Formula: C₂₂H₁₈O₁₀

Purity: %

Color and Shape: Solid

Molecular weight: 442.3723

Ref: IN-DA0035XB

(-)-Epicatechin gallate

CAS: 1257-08-5

(-)-Epicatechin gallate

Purity: 98%

Molecular weight: 442.37g/mol

Ref: 54-OR1007779

(-)-Epicatechin gallate

CAS: 1257-08-5

(-)-Epicatechin gallate

Purity: ≥95%

Molecular weight: 442.37g/mol

Ref: 54-BUP00194

Epicatechin gallate

CAS: 1257-08-5

Formula: C₂₂H₁₈O₁₀

Purity: (HPLC) ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 442.37

Ref: 7W-GP7016

(-)-Epicatechin Gallate

CAS: 1257-08-5

Formula: C₂₂H₁₈O₁₀

Purity: >98.0%(HPLC)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 442.38

Ref: 3B-E0890

(-)-Epicatechin-3-gallate

Controlled Product

CAS: 1257-08-5

Formula: C₂₂H₁₈O₁₀

Color and Shape: Neat

Molecular weight: 442.37

Ref: 04-C13174700

Epicatechin gallate

CAS: 1257-08-5

(-)-Epicatechin gallate can effectively stimulates osteoblast differentiation, it has antioxidative effect against lipid peroxidation when phospholipid bilayers are exposed to aqueous oxygen radicals.

Formula: C₂₂H₁₈O₁₀

Purity: 95%~99%

Molecular weight: 442.376

Ref: BP-BP0539

(-)-Epicatechin Gallate

CAS: 1257-08-5

Formula: C₂₂H₁₈O₁₀

Molecular weight: 442.38

Ref: 4Z-C-151012

(-)-Epicatechin gallate

CAS: 1257-08-5

(-)-Epicatechin gallate, a catechin isomer and strong antioxidant, affects membrane proteins and alters gA channel function in bilayers.

Formula: C₂₂H₁₈O₁₀

Purity: 99.16% - 99.93%

Color and Shape: Solid

Molecular weight: 442.37

Ref: TM-T2732

(-)-epicatechin 3-gallate

CAS: 1257-08-5

Oxygen-heterocyclic compound

Formula: C₂₂H₁₈O₁₀

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 442.38

Ref: 5G-89193

(-)-Epicatechin Gallate

Controlled Product

CAS: 1257-08-5

Stability Light Sensitive
Applications One of the catechin isomers and a potent antioxidant that can modulate a wide range of membrane proteins. Its bilayer-modifying potency was tested using gramicidin A (gA) channels as probes. All the catechins alter gA channel function and modify bilayer properties, with a 500-fold range in potency. The gallate group causes current block, as evident by brief downward current transitions.
References Ingolfsson, H., et al.: FEBS Lett., 585, 3101 (2011),

Formula: C₂₂H₁₈O₁₀

Color and Shape: White To Off-White

Molecular weight: 442.37

Ref: TR-E582265

(-)-Epicatechin gallate

CAS: 1257-08-5

(-)-Epicatechin gallate is a type of catechin, which is a polyphenolic compound primarily sourced from green tea leaves. This compound is known for its potent antioxidant properties, which effectively neutralize free radicals, thereby reducing oxidative stress and potentially preventing cellular damage.

Formula: C₂₂H₁₈O₁₀

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 442.37 g/mol

Ref: 3D-FE22721

(-)-Epicatechin Gallate-13C3

Controlled Product

CAS: 1257-08-5

Formula: C₃C₁₉H₁₈O₁₀

Color and Shape: Neat

Molecular weight: 445.35

Ref: TR-E582267