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CAS 125700-33-6

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N-(9-fluorenylmethoxycarbonyl)glycine-15N

Description:
N-(9-fluorenylmethoxycarbonyl)glycine-15N, commonly referred to as Fmoc-Gly-15N, is a derivative of glycine where the amino group is protected by the 9-fluorenylmethoxycarbonyl (Fmoc) group, and the nitrogen atom is isotopically labeled with nitrogen-15. This compound is primarily used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS), where the Fmoc group serves as a protective group that can be easily removed under basic conditions. The incorporation of the nitrogen-15 isotope allows for applications in NMR spectroscopy and other analytical techniques, providing insights into molecular structure and dynamics. The presence of the Fmoc group enhances the solubility and stability of the amino acid during synthesis. Overall, Fmoc-Gly-15N is a valuable tool in the field of organic chemistry and biochemistry for the synthesis of labeled peptides and proteins, facilitating research in various biochemical applications.
Formula:C17H15NO4
Synonyms:
  • N-(9-Fluorenylmethoxycarbonyl)glycine-1-13C-15N
  • Fmoc-[15N]Gly-OH
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