CAS 125700-34-7

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-tyrosine-15N

Description:

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-tyrosine-15N, commonly referred to as Fmoc-L-Tyr-15N, is a derivative of the amino acid tyrosine, which is modified with a fluorenylmethoxycarbonyl (Fmoc) protecting group. This compound is characterized by its incorporation of a stable nitrogen isotope, 15N, which is often used in research to trace nitrogen in biological systems or to study protein synthesis. The Fmoc group serves as a protective moiety that facilitates the synthesis of peptides by preventing unwanted reactions at the amino group during solid-phase peptide synthesis. The presence of the fluorenyl group contributes to the compound's stability and solubility in organic solvents. Fmoc-L-Tyr-15N is typically utilized in biochemical and pharmaceutical research, particularly in the synthesis of labeled peptides for various applications, including drug development and metabolic studies. Its unique isotopic labeling allows for enhanced detection and analysis in mass spectrometry and NMR spectroscopy.

Formula: C₂₄H₂₁NO₅

InChI: InChI=1S/C24H21NO5/c26-16-11-9-15(10-12-16)13-22(23(27)28)25-24(29)30-14-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-12,21-22,26H,13-14H2,(H,25,29)(H,27,28)/t22-/m0/s1/i25+1

InChI key: InChIKey=SWZCTMTWRHEBIN-LJSUXKQBSA-N

SMILES: C(OC([15NH][C@@H](CC1=CC=C(O)C=C1)C(O)=O)=O)C2C=3C(C=4C2=CC=CC4)=CC=CC3

Synonyms:

• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-tyrosine-15N
• L-Tyrosine-15N, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-

L-Tyrosine-15N, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-

CAS: 125700-34-7

Formula: C₂₄H₂₁NO₅

Molecular weight: 404.4206

Ref: IN-DA000OI2