CAS 1257083-94-5

Heronamide C

CAS: 1257083-94-5

Heronamide C, a polyketide macrolactam antifungal agent synthesized by marine Actinomycetes, exhibits selective toxicity by inhibiting growth and promoting abnormal cell wall material accumulation in wild-type fission yeast cells (MIC = 0.13-0.28 μM), without affecting Gram-positive bacteria or human cancer cell lines, HeLa and MDA-MB-231. At 20 μM, it triggers reversible morphological alterations, notably the development of large intracellular structures, in HeLa cells.

Formula: C₂₉H₃₉NO₃

Color and Shape: Solid

Molecular weight: 449.635

Ref: TM-TN7557