CAS 125770-94-7

Acetophenone-13C6

CAS: 125770-94-7

Acetophenone-13C6

Purity: 98%

Ref: 54-OR1037109

Acetophenone-13C6

Controlled Product

CAS: 125770-94-7

Applications Acetophenone-13C6 is an intermediate in synthesizing Ibuprofen-13C6 (I140003), a labelled Ibuprofen. It is a selective cyclooxygenase inhibitor (IC50=14.9uM). Inhibits PGH synthase-1 and PGH synthase-2 with comparable potency.
References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986); Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993); Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998)

Formula: C₂₁₃C₆H₈O

Color and Shape: Neat

Molecular weight: 126.1

Ref: TR-A164016

Acetophenone-13C6

CAS: 125770-94-7

Acetophenone-13C6 is a potent inhibitor of protein kinases and has shown potential as an anticancer agent. It is an analog of rifampicin, a well-known antibiotic used to treat tuberculosis. Acetophenone-13C6 has been found to induce apoptosis in human cancer cells, making it a promising candidate for cancer treatment. This compound has also been detected in the urine of Chinese cancer patients, indicating its potential as a biomarker for tumor diagnosis and monitoring. Acetophenone-13C6 inhibits the activity of various kinases involved in cancer cell proliferation and survival, making it a valuable tool for studying kinase signaling pathways and developing new kinase inhibitors.

Formula: C₈H₈O

Purity: Min. 95%

Molecular weight: 126.1 g/mol

Ref: 3D-AFA77094