CAS 1258-84-0
:Pristimerin
Description:
Pristimerin is a naturally occurring triterpenoid compound, primarily derived from various plant sources, particularly those in the Celastraceae family. It is characterized by its complex molecular structure, which includes multiple rings and functional groups, contributing to its biological activity. Pristimerin exhibits a range of pharmacological properties, including anti-inflammatory, anti-cancer, and anti-parasitic effects, making it a subject of interest in medicinal chemistry and pharmacology. The compound has been studied for its potential therapeutic applications, particularly in the treatment of diseases such as cancer and malaria. Its mechanism of action often involves the modulation of various signaling pathways and the induction of apoptosis in cancer cells. Additionally, pristimerin's lipophilic nature allows it to interact effectively with cellular membranes, enhancing its bioavailability and efficacy. As research continues, the exploration of pristimerin's full potential and its derivatives may lead to the development of novel therapeutic agents.
Formula:C30H40O4
InChI:InChI=1S/C30H40O4/c1-18-19-8-9-22-28(4,20(19)16-21(31)24(18)32)13-15-30(6)23-17-27(3,25(33)34-7)11-10-26(23,2)12-14-29(22,30)5/h8-9,16,23,32H,10-15,17H2,1-7H3/t23-,26-,27-,28+,29-,30+/m1/s1
InChI key:InChIKey=JFACETXYABVHFD-WXPPGMDDSA-N
SMILES:C[C@@]12[C@](C)([C@]3([C@@](C)(CC1)CC[C@](C(OC)=O)(C)C3)[H])CC[C@]4(C)C2=CC=C5C4=CC(=O)C(O)=C5C
Synonyms:- 2-Picenecarboxylic acid, 1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydro-10-hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-, methyl ester, (2R,4aS,6aS,12bR,14aS,14bR)-
- 2-Picenecarboxylic acid, 1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydro-10-hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-, methyl ester, [2R-(2α,4aβ,6aβ,12bβ,14aα,14bβ)]-
- 24,25,26-Trinoroleana-1(10),3,5,7-tetraen-29-oic acid, 3-hydroxy-9,13-dimethyl-2-oxo-, methyl ester, (9β,13α,14β,20α)-
- 24-Nor-D:A-friedooleana-1(10),3,5,7-tetraen-29-oic acid, 3-hydroxy-2-oxo-, methyl ester
- Celastrol, methyl ester
- Celastrol-methylether
- D:A-Friedo-24-noroleana-1(10),3,5,7-tetraen-29-oic acid, 3-hydroxy-2-oxo-, methyl ester, (20alpha)-
- D:A-Friedo-24-noroleana-1(10),3,5,7-tetraen-29-oic acid, 3-hydroxy-2-oxo-, methyl ester, (20α)-
- Methyl 10-Hydroxy-2,4A,6A,9,12B,14A-Hexamethyl-11-Oxo-1,2,3,4,4A,5,6,6A,11,12B,13,14,14A,14B-Tetradecahydropicene-2-Carboxylate
- NSC 99281
- methyl (2R,4aS,6aS,12bR,14aS,14bR)-10-hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydropicene-2-carboxylate
- See more synonyms
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Found 7 products.
Pristimerin
CAS:<p>Pristimerin has anticancer properties, counters hypoxia-induced cancer spread, and reduces inflammation by inhibiting ROS/IKK/NF-κB pathways.</p>Formula:C30H40O4Purity:98.59% - 99.79%Color and Shape:SolidMolecular weight:464.64Pristimerin
CAS:Carboxylic acid with additional oxygen functionsFormula:C30H40O4Purity:≥ 98.0 % (HPLC)Color and Shape:PowderMolecular weight:464.64Pristimerin
CAS:Controlled Product<p>Pristimerin is a natural product that inhibits the activity of the P-glycoprotein (P-gp), which is an efflux pump that exports drugs from cells. The inhibition of P-gp by pristimerin leads to increased accumulation of drugs at higher concentrations in the cells, which can lead to apoptosis. In addition, pristimerin has been shown to increase intracellular ATP levels and inhibit growth factor-β1. This synergistic effect may be useful for treating bowel disease and cancer.</p>Formula:C30H40O4Purity:Min. 95%Color and Shape:SolidMolecular weight:464.64 g/mol
