CAS 125827-86-3

1-(3-fluorophenyl)cyclohexylamine

Description:

1-(3-Fluorophenyl)cyclohexylamine is an organic compound characterized by its cyclohexylamine backbone substituted with a 3-fluorophenyl group. This compound features a cyclohexane ring, which contributes to its hydrophobic properties, and an amine functional group that can participate in hydrogen bonding, influencing its solubility and reactivity. The presence of the fluorine atom on the phenyl ring enhances the compound's lipophilicity and may affect its biological activity, making it of interest in medicinal chemistry. The compound is typically a solid at room temperature and may exhibit moderate stability under standard conditions. Its molecular structure suggests potential applications in pharmaceuticals, particularly in the development of psychoactive substances or as intermediates in organic synthesis. Safety and handling precautions are essential, as with many amines, due to potential toxicity and reactivity. Overall, 1-(3-fluorophenyl)cyclohexylamine is a compound of interest for further research in various chemical and biological contexts.

Formula: C₁₂H₁₆FN

InChI: InChI=1/C12H16FN/c13-11-6-4-5-10(9-11)12(14)7-2-1-3-8-12/h4-6,9H,1-3,7-8,14H2

SMILES: C1CCC(CC1)(c1cccc(c1)F)N

Synonyms:

• 1-(3-Fluorophenyl)cyclohexanamide
• 3-F-Pca
• Cyclohexanamide, 1-(3-fluorophenyl)-
• 1-(3-Fluorophenyl)Cyclohexanamine

1-(3-fluorophenyl)cyclohexan-1-amine

CAS: 125827-86-3

Formula: C₁₂H₁₆FN

Purity: 97%

Molecular weight: 193.2605

Ref: IN-DA000OT8

1-(3-Fluorophenyl)Cyclohexan-1-Amine

Controlled Product

CAS: 125827-86-3

1-(3-Fluorophenyl)Cyclohexan-1-Amine is a research chemical that is a noncompetitive NMDA receptor antagonist. It has been shown to have neuroprotective properties in animal models of stroke and traumatic brain injury. 1-(3-Fluorophenyl)Cyclohexan-1-Amine binds to the glutamate site on the NMDA receptor, which prevents the binding of glutamate and reduces excitotoxicity. It also activates the calcium channel and blocks voltage-dependent sodium channels. 1-(3-Fluorophenyl)Cyclohexan-1-Amine also has affinity for other receptors, including sigma receptors and dopamine receptors, but its affinity for these sites is weaker than its affinity for NMDA receptors. This drug may be useful as a pharmacological probe or blocker of NMDA receptors.

Formula: C₁₂H₁₆FN

Purity: Min. 95%

Molecular weight: 193.26 g/mol

Ref: 3D-FF82990