CAS 1258391-29-5

3-(2-Aminothiazolo[5,4-b]pyridin-5-yl)-N-(4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide

CAS: 1258391-29-5

3-(2-Aminothiazolo[5,4-b]pyridin-5-yl)-N-(4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide

Purity: 98%

Molecular weight: 540.62g/mol

Ref: 54-PC1007721

HG-7-85-01-NH2

CAS: 1258391-29-5

HG-7-85-01-NH2, as the ligand for SNIPER(ABL)-033, effectively induces the reduction of BCR-ABL protein. This is achieved through SNIPER(ABL)-033, which connects HG-7-85-01 (an ABL inhibitor) to an LCL161 derivative (an IAP ligand) using a linker, demonstrating a DC50 value of 0.3 μM [1].

Formula: C₂₇H₂₇F₃N₆OS

Color and Shape: Solid

Molecular weight: 540.6

Ref: TM-T84745