CAS 12584-58-6
:insulin from hog pancreas
Description:
Insulin from hog pancreas, identified by the CAS number 12584-58-6, is a polypeptide hormone that plays a crucial role in glucose metabolism and regulation in the body. It is composed of 51 amino acids and is structured as two chains, A and B, linked by disulfide bonds. This form of insulin is derived from porcine (hog) sources, which closely resembles human insulin in its amino acid sequence, making it effective for therapeutic use in diabetes management. The substance is typically administered via injection due to its protein nature, which prevents it from being effective when taken orally. Insulin from hog pancreas is characterized by its ability to lower blood glucose levels by facilitating the uptake of glucose into cells, promoting glycogen synthesis in the liver, and inhibiting gluconeogenesis. It is also known for its relatively short half-life, necessitating multiple doses throughout the day for optimal glycemic control. Overall, this insulin variant has been a significant therapeutic agent in the treatment of diabetes, particularly before the advent of recombinant DNA technology that allows for the production of human insulin.
Formula:C256H381N65O76S6
InChI:InChI=1/C256H381N65O76S6/c1-29-131(23)205(313-193(337)104-258)251(391)317-204(130(21)22)247(387)288-159(75-82-200(347)348)217(357)282-156(71-78-189(262)333)221(361)308-183-116-401-402-117-184-242(382)305-178(111-323)239(379)294-162(88-123(7)8)224(364)295-168(95-140-53-61-146(327)62-54-140)227(367)283-154(69-76-187(260)331)218(358)290-161(87-122(5)6)222(362)285-158(74-81-199(345)346)220(360)302-174(101-190(263)334)234(374)298-170(97-142-57-65-148(329)66-58-142)230(370)309-182(241(381)304-176(255(396)397)103-192(265)336)115-400-399-114-181(213(353)272-107-194(338)278-153(72-79-197(341)342)216(356)281-151(51-42-84-270-256(266)267)211(351)271-108-195(339)279-166(93-138-46-36-32-37-47-138)226(366)297-167(94-139-48-38-33-39-49-139)229(369)299-171(98-143-59-67-149(330)68-60-143)237(377)320-208(136(28)326)253(393)321-85-43-52-186(321)245(385)286-152(50-40-41-83-257)214(354)277-134(26)254(394)395)311-249(389)203(129(19)20)316-235(375)164(90-125(11)12)292-228(368)169(96-141-55-63-147(328)64-56-141)296-223(363)160(86-121(3)4)289-209(349)133(25)276-215(355)157(73-80-198(343)344)287-246(386)202(128(17)18)315-236(376)165(91-126(13)14)293-232(372)173(100-145-106-269-120-275-145)301-238(378)177(110-322)280-196(340)109-273-212(352)180(113-398-403-118-185(310-243(183)383)244(384)319-207(135(27)325)252(392)306-179(112-324)240(380)318-206(132(24)30-2)250(390)312-184)307-225(365)163(89-124(9)10)291-231(371)172(99-144-105-268-119-274-144)300-219(359)155(70-77-188(261)332)284-233(373)175(102-191(264)335)303-248(388)201(127(15)16)314-210(350)150(259)92-137-44-34-31-35-45-137/h31-39,44-49,53-68,105-106,119-136,150-186,201-208,322-330H,29-30,40-43,50-52,69-104,107-118,257-259H2,1-28H3,(H2,260,331)(H2,261,332)(H2,262,333)(H2,263,334)(H2,264,335)(H2,265,336)(H,268,274)(H,269,275)(H,271,351)(H,272,353)(H,273,352)(H,276,355)(H,277,354)(H,278,338)(H,279,339)(H,280,340)(H,281,356)(H,282,357)(H,283,367)(H,284,373)(H,285,362)(H,286,385)(H,287,386)(H,288,387)(H,289,349)(H,290,358)(H,291,371)(H,292,368)(H,293,372)(H,294,379)(H,295,364)(H,296,363)(H,297,366)(H,298,374)(H,299,369)(H,300,359)(H,301,378)(H,302,360)(H,303,388)(H,304,381)(H,305,382)(H,306,392)(H,307,365)(H,308,361)(H,309,370)(H,310,383)(H,311,389)(H,312,390)(H,313,337)(H,314,350)(H,315,376)(H,316,375)(H,317,391)(H,318,380)(H,319,384)(H,320,377)(H,341,342)(H,343,344)(H,345,346)(H,347,348)(H,394,395)(H,396,397)(H4,266,267,270)/t131-,132-,133-,134-,135?,136?,150-,151-,152-,153-,154-,155-,156-,157-,158-,159-,160-,161-,162-,163-,164-,165-,166-,167-,168-,169-,170-,171-,172-,173-,174-,175-,176-,177-,178-,179-,180-,181-,182-,183-,184-,185-,186-,201-,202-,203-,204-,205-,206-,207-,208-/m0/s1
Synonyms:- Insulin From Porcine Pancreas
- Insulin, Zinc, Porcine
- Insulin porcine pancreas
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Found 6 products.
INSULIN PORCINE FOR SYSTEM SUITABILITY CRS
CAS:<p>INSULIN PORCINE FOR SYSTEM SUITABILITY CRS</p>Formula:C256H381N65O76S6Insulin Pork
CAS:<p>Insulin and its salts</p>Formula:C256H381N65O76S6Color and Shape:White Off-White Crystalline PowderMolecular weight:5773.62709Insulin Porcine
CAS:Formula:C256H381N65O76S6Purity:≥ 97.0%Color and Shape:White lyophilized powderMolecular weight:5777.59Insulin (Pork)
CAS:<p>Insulin is a hormone that regulates the metabolism of glucose in the body. Insulin is produced by beta cells in the pancreas and released into the blood following a meal. The insulin binds to receptors on cells, causing them to take up glucose from blood for energy or storage. When there is insufficient insulin, glucose builds up in the bloodstream and causes an increase in blood sugar levels. Insulin injections are used to control the level of glucose in people with type 1 diabetes and type 2 diabetes who cannot produce insulin themselves or those who need additional insulin due to other conditions such as pancreatitis or liver disease. The most common way of administering insulin is by injection subcutaneously (underneath the skin). The absorption rate varies depending on where it is injected, but it takes approximately 10 minutes for an injection site to become usable again after an injection has been given. The pharmacokinetic properties of insulin are dependent on pH and temperature; it's most stable at pH 7-8 and at low temperatures</p>Formula:C256H381N65O76S6Purity:Min. 95%Molecular weight:5,777.54 g/molRef: IN-DA009AQE
Discontinued product
