CAS 1259305-29-7: Aripiprazole lauroxil

Description: Aripiprazole lauroxil is an atypical antipsychotic medication primarily used for the treatment of schizophrenia and as an adjunct for major depressive disorder. It is a long-acting injectable formulation of aripiprazole, designed to provide sustained therapeutic effects with less frequent dosing compared to oral formulations. The substance is characterized by its prodrug nature, which means it is metabolized in the body to release the active form, aripiprazole. This compound exhibits a unique mechanism of action, functioning as a partial agonist at dopamine D2 receptors and serotonin 5-HT1A receptors, while acting as an antagonist at 5-HT2A receptors. This dual activity helps to stabilize mood and reduce psychotic symptoms. Aripiprazole lauroxil is typically administered via intramuscular injection, allowing for a gradual release into the bloodstream. Its pharmacokinetics, including absorption, distribution, metabolism, and excretion, are designed to optimize patient adherence and minimize fluctuations in drug levels, contributing to its efficacy in managing chronic psychiatric conditions.

Formula: C₃₆H₅₁Cl₂N₃O₄

InChI: InChI=1S/C36H51Cl2N3O4/c1-2-3-4-5-6-7-8-9-10-16-35(43)45-28-41-33-27-30(19-17-29(33)18-20-34(41)42)44-26-12-11-21-39-22-24-40(25-23-39)32-15-13-14-31(37)36(32)38/h13-15,17,19,27H,2-12,16,18,20-26,28H2,1H3

InChI key: InChIKey=DDINXHAORAAYAD-UHFFFAOYSA-N

SMILES: O=C(OCN1C(=O)CCC2=CC=C(OCCCCN3CCN(C=4C=CC=C(Cl)C4Cl)CC3)C=C21)CCCCCCCCCCC

Aripiprazole Lauroxil

CAS: 1259305-29-7

Aripiprazole lauroxil, the N-acyloxymethyl prodrug form of aripiprazole, a long-acting injectable (LAI) antipsychotic.

• Formula: C₃₆H₅₁Cl₂N₃O₄
• Purity: 98.06%
• Color and Shape: Solid
• Molecular weight: 660.71

Dodecanoic acid, [7-[4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2-oxo-1(2H)-quinolinyl]methyl ester

CAS: 1259305-29-7

• Formula: C₃₆H₅₁Cl₂N₃O₄
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 660.7138

Aripiprazole Lauroxil

CAS: 1259305-29-7

• Purity: 98.06%
• Molecular weight: 660.71g/mol

Aripiprazole lauroxil

CAS: 1259305-29-7

• Formula: C₃₆H₅₁N₃O₄Cl₂
• Color and Shape: Neat
• Molecular weight: 660.71

Aripiprazole lauroxil

CAS: 1259305-29-7

Aripiprazole lauroxil is a long-acting injectable antipsychotic that belongs to the class of drugs known …

• Formula: C₃₆H₅₁Cl₂N₃O₄
• Purity: Min. 95%
• Molecular weight: 660.71 g/mol