CAS 125941-87-9

(5R)-8-chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-ol hydrochloride (1:1)

Description:

(5R)-8-chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-ol hydrochloride is a chemical compound characterized by its complex bicyclic structure, which includes a benzazepine core. This compound features a chlorine atom and a hydroxyl group, contributing to its potential biological activity. The presence of a phenyl group and a methyl group enhances its lipophilicity, which may influence its pharmacokinetic properties. As a hydrochloride salt, it is typically more soluble in water than its free base form, facilitating its use in pharmaceutical formulations. The stereochemistry indicated by the (5R) designation suggests specific spatial arrangements of atoms, which can significantly affect the compound's interaction with biological targets. This compound may exhibit various pharmacological effects, making it of interest in medicinal chemistry, particularly in the development of therapeutic agents. However, detailed studies on its efficacy, safety, and mechanism of action would be necessary to fully understand its potential applications.

Formula: C₁₇H₁₉Cl₂NO

InChI: InChI=1/C17H18ClNO.ClH/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12;/h2-6,9-10,15,20H,7-8,11H2,1H3;1H/t15-;/m1./s1

SMILES: CN1CCc2cc(c(cc2[C@H](C1)c1ccccc1)O)Cl.Cl

Synonyms:

• 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-, (5R)-, hydrochloride (1:1)

SCH 23390 (hydrochloride)

CAS: 125941-87-9

Formula: C₁₇H₁₉Cl₂NO

Purity: 98%

Color and Shape: Solid

Molecular weight: 324.2449

Ref: IN-DA000QKQ

SCH-23390 hydrochloride

CAS: 125941-87-9

SCH-23390 hydrochloride

Purity: ≥98%

Molecular weight: 324.24g/mol

Ref: 54-BUP05425

SCH-23390 hydrochloride

CAS: 125941-87-9

SCH-23390 hydrochloride (R-(+)-SCH23390 hydrochloride) is an effective dopamine receptor antagonist, and for the D1(Ki=0.2 nM) and D5(Ki=0.3 nM).

Formula: C₁₇H₁₉Cl₂NO

Purity: 98% - 99.83%

Color and Shape: Solid

Molecular weight: 324.24

Ref: TM-T4369

SCH 23390 hydrochloride

CAS: 125941-87-9

Antagonist of D1-like dopamine receptor subtypes, D1 and D5 (Ki values 0.2 and 0.3 nM respectively). Agonist of serotonin receptors 5-HT1C and 5-HT2C (Ki values 6.3 nM and 9.3 nM respectively). Used to study the topography of D1 receptors in humans and animals. Reduces seizures in response to chemoconvulsants and has also been studied in other neurological disorders.

Formula: C₁₇H₁₈ClNO·HCl

Purity: Min. 95%

Color and Shape: White/Off-White Solid

Molecular weight: 324.24

Ref: 3D-FC139019

(R)-(+)-Sch 23390 Hydrochloride

Controlled Product

CAS: 125941-87-9

Formula: C₁₇H₁₈ClNO·HCl

Color and Shape: Neat

Molecular weight: 324.245

Ref: TR-S199925