CAS 125974-72-3

Intoplicine

Description:

Intoplicine, with the CAS number 125974-72-3, is a chemical compound that has garnered interest primarily in the field of medicinal chemistry. It is characterized as a synthetic compound with a complex molecular structure, which contributes to its pharmacological properties. Intoplicine is known to exhibit activity as a selective antagonist of certain neurotransmitter receptors, particularly in the central nervous system. This selectivity may influence its potential therapeutic applications, particularly in the treatment of neurological disorders. The compound's solubility, stability, and bioavailability are critical factors that affect its efficacy and safety profile. Additionally, research into Intoplicine has explored its interactions with various biological targets, which may provide insights into its mechanism of action. As with many chemical substances, understanding its pharmacokinetics and pharmacodynamics is essential for evaluating its potential use in clinical settings. Overall, Intoplicine represents a compound of interest for further investigation in drug development and therapeutic applications.

Formula: C₂₁H₂₄N₄O

InChI: InChI=1S/C21H24N4O/c1-13-12-23-21(22-9-4-10-25(2)3)19-18-16-7-6-15(26)11-14(16)5-8-17(18)24-20(13)19/h5-8,11-12,24,26H,4,9-10H2,1-3H3,(H,22,23)

InChI key: InChIKey=QROONAIPJKQFMC-UHFFFAOYSA-N

SMILES: N(CCCN(C)C)C1=C2C=3C=4C(C=CC3NC2=C(C)C=N1)=CC(O)=CC4

Synonyms:

• 11-((3-(Dimethylamino)propyl)amino)-8-methyl-7H-benzo(e)pyrido(4,3-b)indol-3-ol
• 7H-Benzo(e)pyrido(4,3-b)indol-3-ol, 11-((3-(dimethylamino)propyl)amino)-8-methyl-
• Intoplicine [INN]
• Rp 60475
• Unii-Fb2Cin6Hmi
• Intoplicine

Intoplicine

CAS: 125974-72-3

Intoplicine is an active analogue of the antibiotic erythromycin. It has inhibitory properties against a wide range of bacteria and fungi, including Bacillus subtilis, Staphylococcus aureus, and Candida albicans. Intoplicine inhibits fatty acid synthesis in bacterial cells by binding to the enzyme hydroxylase. Intoplicine also has cytotoxic effects in human HL-60 and K562 cells. The mechanism of action is not yet known but may be due to inhibition of DNA synthesis or protein synthesis by binding to the cell membrane. Intoplicine binds to the lipid bilayer and alters its permeability.

Formula: C₂₁H₂₄N₄O

Purity: Min. 95%

Molecular weight: 348.4 g/mol

Ref: 3D-AFA97472

Intoplicine

CAS: 125974-72-3

Intoplicine is an inhibitor of DNA topoisomerase I and II.

Formula: C₂₁H₂₄N₄O

Purity: 98%

Color and Shape: Solid

Molecular weight: 348.44

Ref: TM-T15586