CAS 125989-12-0

L-659 877

Description:

L-659,877, with the CAS number 125989-12-0, is a chemical compound that belongs to the class of selective serotonin reuptake inhibitors (SSRIs). It is primarily known for its potential use in the treatment of various psychiatric disorders, particularly depression and anxiety. The compound exhibits a high affinity for serotonin transporters, which facilitates the increase of serotonin levels in the synaptic cleft, thereby enhancing mood and emotional stability. L-659,877 is characterized by its specific molecular structure, which contributes to its pharmacological activity. It is typically administered in a controlled dosage to minimize side effects, which may include gastrointestinal disturbances, insomnia, or sexual dysfunction. Research into L-659,877 has focused on its efficacy and safety profile, as well as its mechanism of action at the molecular level. As with many SSRIs, the therapeutic effects may take several weeks to manifest, and it is essential for patients to be monitored by healthcare professionals during treatment.

Formula: C₃₈H₅₀N₈O₇S

InChI: InChI=1/C38H50N8O7S/c1-22(2)17-29-37(52)44-28(15-16-54-3)36(51)43-27(13-14-32(39)47)35(50)46-31(19-24-20-40-26-12-8-7-11-25(24)26)38(53)45-30(18-23-9-5-4-6-10-23)34(49)41-21-33(48)42-29/h4-12,20,22,27-31,40H,13-19,21H2,1-3H3,(H2,39,47)(H,41,49)(H,42,48)(H,43,51)(H,44,52)(H,45,53)(H,46,50)

SMILES: CC(C)CC1C(=NC(CCSC)C(=NC(CCC(=N)O)C(=NC(Cc2c[nH]c3ccccc23)C(=NC(Cc2ccccc2)C(=NCC(=N1)O)O)O)O)O)O

Synonyms:

• L-659,877 Synthetic >98% Nk2 Tachykinin Recept
• cyclo(D-glutaminyltryptophyl-L-phenylalanylglycyl-L-leucyl-L-methionyl)
• Cyclo(Glutaminyltryptophylphenylalanylglycylleucylmethionyl)

L 659,877

CAS: 125989-12-0

L 659,877 is an antagonist of the Tachykinin and neurokinin-2 receptor.

Formula: C₃₈H₅₀N₈O₇S

Purity: 98%

Color and Shape: Solid

Molecular weight: 762.92

Ref: TM-T20148

Cyclo(-Gln-Trp-Phe-Gly-Leu-Met)

CAS: 125989-12-0

Cyclo(-Gln-Trp-Phe-Gly-Leu-Met) is a cyclic peptide that has been shown to have cholinergic properties and low potency. It has a chemical structure that consists of the amino acids Gln, Trp, Phe, Gly, Leu, and Met. Cyclo(-Gln-Trp-Phe-Gly-Leu-Met) has been shown to increase bladder capacity in animal models. The mechanism of action of this drug is not fully understood but it may involve the adenosine A3 receptor and gamma aminobutyric acid (GABA). Cyclo(-Gln-Trp-Phe-Gly-Leu-Met) also inhibits DNA replication by interacting with intermolecular hydrogen bonding sites on the DNA molecule.

Formula: C₃₈H₅₀N₈O₇S

Purity: Min. 95%

Molecular weight: 762.92 g/mol

Ref: 3D-FC110416