CAS 126-07-8: Griseofulvin

Description: Griseofulvin is an antifungal medication primarily used to treat dermatophyte infections, particularly those affecting the skin, hair, and nails. It is derived from the mold Penicillium griseofulvum and functions by inhibiting fungal cell mitosis, thereby preventing the growth and reproduction of fungi. Griseofulvin is characterized by its crystalline structure and is typically administered orally. It is poorly soluble in water but more soluble in organic solvents, which influences its absorption and bioavailability. The substance is known for its relatively long half-life, allowing for once-daily dosing in many cases. Common side effects may include gastrointestinal disturbances, headache, and potential allergic reactions. Griseofulvin is contraindicated in certain populations, such as pregnant individuals, due to potential teratogenic effects. Its effectiveness is often assessed through clinical evaluation and laboratory tests to confirm the presence of susceptible fungal species. Overall, Griseofulvin remains a significant therapeutic option in the management of specific fungal infections.

Formula: C₁₇H₁₇ClO₆

InChI: InChI=1S/C17H17ClO6/c1-8-5-9(19)6-12(23-4)17(8)16(20)13-10(21-2)7-11(22-3)14(18)15(13)24-17/h6-8H,5H2,1-4H3/t8-,17+/m1/s1

InChI key: InChIKey=DDUHZTYCFQRHIY-RBHXEPJQSA-N

SMILES: O=C1C=C(OC)C2(OC=3C(Cl)=C(OC)C=C(OC)C3C2=O)C(C)C1

Synonyms:

• (1′S,6′R)-7-Chloro-2′,4,6-trimethoxy-6′-methylspiro[benzofuran-2(3H),1′-[2]cyclohexene]-3,4′-dione
• (2R,6'S)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohex[2]ene]-3,4'-dione
• (2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohex[2]ene]-3,4'-dione
• (2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohexane]-3,4'-dione
• (2S,6'S)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohex[2]ene]-3,4'-dione
• 7-Chloro-2',4,6-trimethoxy-6'-methylspiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione
• 7-Chloro-2',4,6-trimethoxy-6'β-methylspiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione
• 7-Chloro-2′,4,6-trimethoxy-6′β-methylspiro[benzofuran-2(3H),1′-[2]cyclohexene]-3,4′-dione
• 7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohex[2]ene]-3,4'-dione
• Amudane
• Curling factor
• Fulcin
• Fulvicin
• Fulvicin Bolus
• Fulvicin P/G
• Fulvicin U/F
• Fulvidex
• Fulvina
• Fulvinil
• Fulvistatin
• Gricin
• Grifulin
• Grifulvin
• Grifulvin V
• Gris-PEG
• Grisactin
• Grisefulin
• Griseofulvin Powder
• Griseofulvina
• Griseofulvine
• Griseovin
• Grisofulvin
• Grisovin
• Grisovin FP
• Grysio
• Idifulvin
• Lamoryl
• Likuden
• Neo-Fulcin
• Polygris
• Poncyl
• Poncyl FP
• Spiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione, 7-chloro-2',4,6-trimethoxy-6'-methyl-, (1'S,6'R)-
• Spiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione, 7-chloro-2',4,6-trimethoxy-6'-methyl-, (1'S-trans)-
• Spiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione, 7-chloro-2',4,6-trimethoxy-6'β-methyl-
• Spiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione,7-chloro-2',4,6-trimethoxy-6'-methyl-, (1'R-trans)-
• Spiro[benzofuran-2(3H),1′-[2]cyclohexene]-3,4′-dione, 7-chloro-2′,4,6-trimethoxy-6′-methyl-, (1′S,6′R)-
• Spiro[benzofuran-2(3H),1′-[2]cyclohexene]-3,4′-dione, 7-chloro-2′,4,6-trimethoxy-6′-methyl-, (1′S-trans)-
• Spiro[benzofuran-2(3H),1′-[2]cyclohexene]-3,4′-dione, 7-chloro-2′,4,6-trimethoxy-6′β-methyl-
• Spirofulvin
• Sporostatin
• Xuanjing
• (+)-Griseofulvin

(+)-Griseofulvin

CAS: 126-07-8

• Formula: C₁₇H₁₇ClO₆
• Purity: >95.0%(HPLC)(qNMR)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 352.77

(+)-Griseofulvin, 97%

CAS: 126-07-8

Griseofulvin is an antifungal drug. It is used both in animal and in humans, to …

• Formula: C₁₇H₁₉ClO₆
• Purity: 97%
• Color and Shape: White, Powder
• Molecular weight: 354.78

Griseofulvin

CAS: 126-07-8

• Formula: C₁₇H₁₇ClO₆
• Purity: 99.11%
• Color and Shape: Brownish. Powder
• Molecular weight: 353.0

Griseofulvin RS

CAS: 126-07-8

• Formula: C₁₇H₁₇ClO₆
• Molecular weight: 352.7663

Griseofulvin Permeability Diameter

CAS: 126-07-8

Antibiotics nesoi

• Formula: C₁₇H₁₇ClO₆
• Color and Shape: White Off-White Powder
• Molecular weight: 352.77

Griseofulvin

CAS: 126-07-8

Antibiotics nesoi

• Formula: C₁₇H₁₇ClO₆
• Color and Shape: White Cream Powder
• Molecular weight: 352.07137

Griseofulvin

CAS: 126-07-8

Griseofulvin (Fulvicin) is an antifungal agent used in the treatment of TINEA infections.

• Formula: C₁₇H₁₇ClO₆
• Purity: 95.83% - 98.12%
• Color and Shape: Stout Octahedra Or Rhombs From Benzene
• Molecular weight: 352.77

(+)-Griseofulvin

CAS: 126-07-8

• Formula: C₁₇H₁₇ClO₆
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 352.7663

(+)-Griseofulvin

CAS: 126-07-8

• Molecular weight: 352.77g/mol

Griseofulvin, EP grade

CAS: 126-07-8

• Formula: C₁₇H₁₇ClO₆
• Purity: ≤ 0.75%
• Color and Shape: White or pale yellow powder
• Molecular weight: 352.77

Griseofulvin-13C-d3

CAS: 126-07-8

• Formula: C₁₆₁₃CH₁₄D₃ClO₆
• Color and Shape: White To Off-White Solid
• Molecular weight: 356.78

Griseofulvin

CAS: 126-07-8

• Formula: C₁₇H₁₇ClO₆
• Purity: 97.0 - 102.0 % (dried basis)
• Color and Shape: White or off-white powder
• Molecular weight: 352.77

Griseofulvin

CAS: 126-07-8

• Formula: C₁₇H₁₇ClO₆
• Color and Shape: White To Off-White Solid
• Molecular weight: 352.77

Griseofulvin 100 µg/mL in Acetonitrile

CAS: 126-07-8

• Formula: C₁₇H₁₇ClO₆
• Color and Shape: Single Solution
• Molecular weight: 352.77

Griseofulvin

CAS: 126-07-8

• Formula: C₁₇H₁₇ClO₆
• Color and Shape: Neat
• Molecular weight: 352.77

Griseofulvin

CAS: 126-07-8

• Formula: C₁₇H₁₇ClO₆
• Color and Shape: Neat
• Molecular weight: 352.77

(2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H-spiro[1-benzofuran-2,1'-cyclohexan]-2'-ene-3,4'-dione

CAS: 126-07-8

• Purity: 98.0%
• Color and Shape: Solid
• Molecular weight: 352.7699890136719

Griseofulvin

CAS: 126-07-8

Applications It is an antifungal drug. It is used both in animal and in humans, …

• Formula: C₁₇H₁₇ClO₆
• Color and Shape: Off-White
• Molecular weight: 352.77

Griseofulvin - Bio-X ™

CAS: 126-07-8

Griseofulvin is an antifungal drug used to treat several types of dermatophytosis (ringworm). This includes …

• Formula: C₁₇H₁₇ClO₆
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 352.77 g/mol

Griseofulvin

CAS: 126-07-8

Anti-fungal; microtubule polymerization inhibitor

• Formula: C₁₇H₁₇ClO₆
• Purity: Min. 97 Area-%
• Color and Shape: Powder
• Molecular weight: 352.77 g/mol