CAS 1260141-27-2

TAK438

Description:

TAK-438, with the CAS number 1260141-27-2, is a chemical compound that functions primarily as a proton pump inhibitor (PPI). It is designed to inhibit the activity of the proton pump in the gastric parietal cells, thereby reducing gastric acid secretion. This mechanism makes it useful in the treatment of conditions such as gastroesophageal reflux disease (GERD) and peptic ulcers. TAK-438 is characterized by its ability to provide long-lasting acid suppression, which is beneficial for patients requiring sustained relief from acid-related disorders. The compound is typically administered orally and has been studied for its pharmacokinetic properties, including absorption, distribution, metabolism, and excretion. Its efficacy and safety profile have been evaluated in clinical trials, contributing to its potential therapeutic applications. As with any pharmaceutical agent, it is essential to consider possible side effects and interactions with other medications when prescribing TAK-438.

Formula: C₂₁H₂₀FN₃O₆S

InChI: InChI=1S/C17H16FN3O2S.C4H4O4/c1-19-10-13-9-17(15-6-2-3-7-16(15)18)21(12-13)24(22,23)14-5-4-8-20-11-14;5-3(6)1-2-4(7)8/h2-9,11-12,19H,10H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1+

InChI key: InChIKey=ROGSHYHKHPCCJW-WLHGVMLRSA-N

SMILES: S(=O)(=O)(N1C(=CC(CNC)=C1)C2=C(F)C=CC=C2)C=3C=CC=NC3.C(=C/C(O)=O)\C(O)=O

Synonyms:

• 1H-Pyrrole-3-methanamine, 5-(2-fluorophenyl)-N-methyl-1-(3-pyridinylsulfonyl)-, (2E)-2-butenedioate (1:1)
• 5-(2-Fluorophenyl)-N-methyl-1-(3-pyridinylsulfonyl)-1H-pyrrole-3-methanamine (2E)-2-butenedioate
• 5-(2-Fluorophenyl)-N-methyl-1-(3-pyridinylsulfonyl)-1H-pyrrole-3-methanamine (2E)-2-butenedioate (1:1)
• TAK 438 monofumarate
• Tak-438
• Takecab
• Vocinti
• Vonoprazan fumarate
• Vonaprazan
• TAK438
• Vonaprazan(TAK-438)
• 1-(5-(2-FLUOROPHENYL)-1-(PYRIDIN-4-YLSULFONYL)-1H-PYRROL-3-YL)-N-METHYLMETHANAMINE
• vonoprazan(tak-438)
• Vonoprazan Fumarate-D3Q: What is
• Vorolazan fumarate
• Vonoprazan fumarate API
• Fumarate vonolasan
• Vonoprazan Vonoprazan onoprazan Vonoprazan fumarate
• Vonoprazan Fumarate-D3
• TAK 438; TAK438
• vonoprazan(tak-438)1260141-27-2
• Vonoprazon Fumarate
• 5-(2-Fluorophenyl)-N-methyl-1-(3-pyridinylsulfonyl)-1H-pyrrole-3-methanamine 2-butenedioate (Vonoprazan)
• 4-Aminopyrazolo[3
• TAK-438,1260141-27-2 Fluorine Prazan
• TAK-438 USP/EP/BP
• 5-(2-Fluorophenyl)-N-methyl-1-(3-pyridinylsulfonyl)-1H-pyrrole-3-methanamine 2-butenedioate (Vonoprazan fumarate)
• Vonolazan Fumarate API
• TAK-438 ISO 9001：2015 REACH
• VONOPRAZAN FUMARATE (TAK-438);TAK-438
• 1-[5-(2-fluorophenyl)-1-pyridin-3-ylsulfonylpyrrol-3-yl]-N-methylmethanamine
• DISCONTINUED PLEASE SEE V767013
• Vonoprazan fumarate(TAK-438)
• CS-597
• vonaprazan(TK-438)
• TAK 438,Vonoprazan
• Vonoprazan Fumarate-D3 Q: What is the CAS Number of
• 1-[5-(2-fluorophenyl)-1-pyridin-3-ylsulfonylpyrrol-3-yl]-N-methylmethanamine,(E)-4-oxopent-2-enoic acid
• AK-438
• Wonarazan Fumarate
• 5-(2-Fluorophenyl)-N-methyl-1-(3-pyridinylsulfonyl)-1H-pyrrole-3-methanamine 2-butenedioate
• 1H-Pyrrole-3-methanamine, 5-(2-fluorophenyl)-N-methyl-1-(3-pyridinylsulfonyl)-, 2-butenedioate (1:1)
• fuMarate vonoprazan
• Vonorasen fumarate
• vomoprazan fumarate
• Vonoprazan-025-Salt2
• 5-(2-Fluorophenyl)-N-methyl-1-(3-pyridinylsulfonyl)-1H-pyrrole-3-methanamine 2-butenedioate TAK 438

1H-Pyrrole-3-methanamine, 5-(2-fluorophenyl)-N-methyl-1-(3-pyridinylsulfonyl)-, 2-butenedioate (1:1)

CAS: 1260141-27-2

Formula: C₂₁H₂₀FN₃O₆S

Purity: 98%

Color and Shape: Solid

Molecular weight: 461.4634

Ref: IN-DA000QR8

Vonoprazan-d4 Fumarate

CAS: 1260141-27-2

Formula: C₁₇H₁₂D₄FN₃O₂S·C₄H₄O₄

Color and Shape: White To Off-White Solid

Molecular weight: 349.42 116.07

Ref: 4Z-V-051068

Vonoprazan Fumarate

CAS: 1260141-27-2

Vonoprazan Fumarate

Purity: ≥98%

Molecular weight: 461.46g/mol

Ref: 54-BUP18877

Vonoprazan fumarate

CAS: 1260141-27-2

Vonoprazan fumarate (TAK-438) is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+, ATPase.

Formula: C₁₇H₁₆FN₃O₂S·C₄H₄O₄

Purity: 99.16% - 99.98%

Color and Shape: Solid

Molecular weight: 461.46

Ref: TM-T2404

Vonoprazan-d4 Fumarate

Controlled Product

CAS: 1260141-27-2

Formula: C₁₇H₁₂D₄FN₃O₂S•C₄H₄O₄

Color and Shape: White To Off-White

Molecular weight: 465.49

Ref: TR-V767014

Vonoprazan Fumarate-D3

Controlled Product

CAS: 1260141-27-2

Applications A labeled isotope of Vonoprazan Fumarate (V767010) a novel potassium-​competitive acid blocker for the treatment of acid-​related diseases.
References Luo, Z. et al.: J. Pharm. Biomed. Anal., 149, 133 (2018); Garnock-Jones, K. et al.: Drugs, 75, 439 (2015);

Formula: C₁₇H₁₃D₃FN₃O₂S•C₄H₄O₄

Color and Shape: Neat

Molecular weight: 464.48

Ref: TR-V767012

TAK 438

CAS: 1260141-27-2

Potassium-competitive acid blocker; inhibitor of gastric H+/K+ -ATPase

Formula: C₁₇H₁₆FN₃O₂S•C₄H₄O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 461.46 g/mol

Ref: 3D-FT102406