CAS 1260247-42-4

9,10-Dihydro-5-hydroxy-9,10-dioxo-1-anthracenesulfonamide

Description:

9,10-Dihydro-5-hydroxy-9,10-dioxo-1-anthracenesulfonamide is a synthetic organic compound belonging to the anthracene derivative class. It features a polycyclic aromatic structure, characterized by a fused ring system that contributes to its stability and potential biological activity. The presence of hydroxyl and sulfonamide functional groups enhances its solubility in polar solvents and may influence its reactivity and interaction with biological targets. This compound is of interest in medicinal chemistry due to its potential applications in drug development, particularly in the context of anticancer and antimicrobial agents. Its dioxo groups suggest possible redox activity, which could be relevant in various biochemical pathways. The compound's unique structural features may also allow for specific interactions with enzymes or receptors, making it a candidate for further pharmacological studies. As with many anthracene derivatives, it may exhibit fluorescence properties, which can be useful in imaging and sensing applications. However, detailed studies are necessary to fully elucidate its biological properties and mechanisms of action.

Formula: C₁₄H₉NO₅S

InChI: InChI=1S/C14H9NO5S/c15-21(19,20)10-6-2-4-8-12(10)14(18)7-3-1-5-9(16)11(7)13(8)17/h1-6,16H,(H2,15,19,20)

InChI key: InChIKey=CQBHSRLUQDYPBU-UHFFFAOYSA-N

SMILES: S(N)(=O)(=O)C1=C2C(C(=O)C=3C(C2=O)=CC=CC3O)=CC=C1

Synonyms:

• 1-Anthracenesulfonamide, 9,10-dihydro-5-hydroxy-9,10-dioxo-
• 9,10-Dihydro-5-hydroxy-9,10-dioxo-1-anthracenesulfonamide
• LLL 12

5-Hydroxy-9,10-dioxo-9,10-dihydroanthra

CAS: 1260247-42-4

9,10-Dioxo-5HDA is a potent and selective inhibitor of the voltage-gated potassium channel Kv1.3. 9,10-Dioxo-5HDA inhibits Kv1.3 currents at low micromolar concentrations and blocks the activation of the channel by ATP at nanomolar concentrations. The binding site for 9,10-dioxo-5HDA is located in the pore region of the channel's selectivity filter. In addition to its pharmacological activity, 9,10-dioxo-5HDA has been shown to be an excellent research tool for studying protein interactions with voltage gated ion channels.

Formula: C₁₄H₉NO₅S

Purity: Min. 95%

Molecular weight: 303.29 g/mol

Ref: 3D-KAC24742

LLL12

CAS: 1260247-42-4

LLL12 inhibits STAT3 phosphorylation, boosting Cisplatin and Paclitaxel effects against ovarian cancer cell activities.

Formula: C₁₄H₉NO₅S

Color and Shape: Solid

Molecular weight: 303.29

Ref: TM-T71099