CAS 126054-77-1

(3S,3aR,5R,8R,8aS)-3,8-dihydroxy-8-(hydroxymethyl)-3-methyl-5-[1-methyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-ethyl]-3a,4,5,6,7,8a-hexahydro-1H-azulen-2-one

Description:

The chemical substance with the name "(3S,3aR,5R,8R,8aS)-3,8-dihydroxy-8-(hydroxymethyl)-3-methyl-5-[1-methyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-ethyl]-3a,4,5,6,7,8a-hexahydro-1H-azulen-2-one" and CAS number "126054-77-1" is a complex organic compound characterized by multiple hydroxyl groups, which suggest it may exhibit significant solubility in polar solvents and potential for hydrogen bonding. The presence of a hexahydro-azulenone structure indicates it may possess unique aromatic properties, contributing to its reactivity and stability. The stereochemistry, denoted by the specific configurations at various chiral centers, implies that the compound may exhibit specific biological activities or interactions, making it of interest in pharmaceutical or biochemical applications. Additionally, the presence of a tetrahydropyran moiety suggests potential for further functionalization or derivatization, enhancing its utility in synthetic chemistry. Overall, this compound's intricate structure and functional groups position it as a potentially valuable substance in various chemical and biological contexts.

Formula: C₂₁H₃₆O₁₀

InChI: InChI=1/C21H36O10/c1-19(2,31-18-17(27)16(26)15(25)13(8-22)30-18)10-4-5-21(29,9-23)12-7-14(24)20(3,28)11(12)6-10/h10-13,15-18,22-23,25-29H,4-9H2,1-3H3/t10-,11-,12+,13-,15-,16+,17-,18+,20+,21+/m1/s1

Synonyms:

• Atractyloside A

2(1H)-Azulenone,7-[1-(b-D-glucopyranosyloxy)-1-methylethyl]octahydro-1,4-dihydroxy-4-(hydroxymethyl)-1-methyl-, (1S,3aS,4R,7R,8aR)-

CAS: 126054-77-1

Formula: C₂₁H₃₆O₁₀

Purity: 98%

Color and Shape: Solid

Molecular weight: 448.5045

Ref: IN-DA00IKM2

Atractyloside A

CAS: 126054-77-1

Atractyloside A

Purity: ≥98%

Molecular weight: 448.5g/mol

Ref: 54-BUP07463

Atractyloside A

CAS: 126054-77-1

Formula: C₂₁H₃₆O₁₀

Molecular weight: 448.51

Ref: 7W-GY3291

Atractyloside A

CAS: 126054-77-1

Formula: C₂₁H₃₆O₁₀

Purity: 95%~99%

Molecular weight: 448.509

Ref: BP-BP0218

Atractyloside A

CAS: 126054-77-1

Atractyloside is a glycoside of a kaurene type diterpene that is found in some plants including Atractylis gummifera (ATRACTYLIS); COFFEE; XANTHIUM, and

Formula: C₂₁H₃₆O₁₀

Purity: 99.22% - 99.65%

Color and Shape: Solid

Molecular weight: 448.5

Ref: TM-T3791

Atractyloside A

Controlled Product

CAS: 126054-77-1

Stability Hygroscopic
Applications Atractyloside A is known to inhibit mitochondrial ADP transportation resulting in necrosis. Antimicrobial.
References Stewart, M. et al.: Ther. Drug. Monit., 22, 641 (2000); Federico, B. et al.: J. Nat. Prod., 75 1070 (2012);

Formula: C₂₁H₃₆O₁₀

Color and Shape: Neat

Molecular weight: 448.5

Ref: TR-A794585

atractyloside A

CAS: 126054-77-1

Atractyloside A is a natural toxin that acts as a potent mitochondrial ATP synthase inhibitor. It is derived primarily from plants in the Asteraceae family, notably Atractylis gummifera. The compound functions by binding to the adenine nucleotide translocator (ANT) located on the inner mitochondrial membrane, effectively blocking the exchange of ADP and ATP across this vital barrier. This inhibition disrupts ATP synthesis, inducing cellular energy deficits and potentially leading to apoptosis.

Purity: Min. 95%

Ref: 3D-FA73913